How much glutathione should I take daily for skin whitening?
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81 Citations | Reduced glutathione was significantly decreased, suggesting glutathione depletion due to oxida-tive stress. |
| These results indicate that the 'organ Km' for glutathione in the liver is approximately 0.5 mumol/g of liver, so that the hepatic glutathione conjugation rate is decreased only at severe glutathione depletion. | |
64 Citations | The observed differences in the glutathione and glutathione-related enzyme content between black and yellow (or red) skin provide evidence that the increase of glutathione-reductase activity in the environment of the melanocytes may stimulate the pigment cells to produce phaeomelanin instead of eumelanin pigment. |
50 Citations | These results suggest that glyasperin C and glycyrrhisoflavone could be promising candidates in the design of skin-whitening agents. |
46 Citations | We have found 9 herb extracts to be promising skin whitening agents. |
| We conclude that sc administration of a large dose of GHRH (4 mg) twice daily for 3 months elevates GH and IGF-I concentrations, increases total body water and fat-free mass, reduces total abdominal adiposity, and enhances certain performance measures in healthy aging men but causes local skin reactions. | |
258 Citations | Because of hydrolysis of glutathione by intestinal and hepatic γ-glutamyltransferase, dietary glutathione is not a major determinant of circulating glutathione, and it is not possible to increase circulating glutathione to a clinically beneficial extent by the oral administration of a single dose of 3 g of glutathione. |
| Taken together, this study suggests topical formulations such as creams including SLNs with JSH18 might be an appropriate carrier for skin-whitening agents. | |
57 Citations | The data also suggest that intracellular glutathione levels strongly influence the induction of a post-mitotic phenotype and that, by implication, depletion of glutathione may play a significant role in the progression of cellular ageing in human skin. |
61 Citations | Future studies among subjects diagnosed with an ASD should further explore the pharmacokinetics of glutathione supplementation and evaluate the potential effects of glutathione supplementation upon clinical symptoms. |
34 Citations | Significant decreases in reduced glutathione and increases in oxidized glutathione levels were observed on HA exposure. |
| Blood glutathione is not a good measure of organ glutathione stores when dealing with indirect‐acting glutathione‐depleting substances. | |
| These concepts should lead to reconsideration of some of the conventional approaches to increasing intracellular glutathione levels. |
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