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Experiments using the zinc-responsive fluorophore FuraZin-1 as an indicator of vacuolar zinc levels indicated that Zrc1 is required for the rapid transport of zinc into the vacuole during zinc shock.
The population mean serum zinc concentration is a useful indicator of the successful delivery and absorption of zinc supplements in children.
The zinc inhibition is much more pronounced than was previously reported, with dissociation constants in the low nanomolar range.
The results from depletion/repletion studies indicate that serum zinc concentrations respond appreciably to severe dietary zinc restriction, although there is considerable interindividual variation in these responses.
The model is able to explain the experimental evidence collected so far in our laboratory: high zinc yields are only obtained if the zinc/oxygen mixture is strongly diluted with inert gas.
Zinc intake was inconsistently associated with markers of serum zinc concentration.
It is thought that zinc may play a part in this process.
In five of six subjects a drop in urinary zinc to below 150 micrograms/day was noted before a decrease in plasma zinc to less than 70 micrograms/100 g, indicating that urinary zinc responds more rapidly than plasma zinc to dietary changes and may be useful for evaluating zinc nutriture.
Mass fortification of zinc may be a cost-effective strategy to overcome zinc deficiency.
A zinc tolerance determination of this kind may be of value in differentiating clinical entities in which zinc deficiency may occur.
S. viridis tolerance of high zinc concentrations, as well as its capacity to accumulate zinc in roots and shoots, suggests the plant can be used for phytoremediation of zinc polluted soils.
Zinc status of the individual may also influence adjustments in fractional zinc absorption.
Serum zinc is thought to be a reasonable indicator of zinc status.
The assay is quick, convenient, and in principle measures functionally available zinc.
Our data indicate that caudal fin zinc concentrations are a good indicator of zinc status.
Zinc absorption in humans could be improved by zinc complexation with gluconate.
The results are consistent with a model of zinc tolerance in which zinc is complexed with citrate in the vacuole.