What is asap3-kv (fluorescent voltage sensor)?
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ASAP3-Kv is a genetically encoded voltage indicator (GEVI) that is used to track transmembrane voltage changes in cells undergoing motion. It is a high-performance ratiometric GEVI that combines a high-gain green fluorescent protein (GFP) with a voltage-independent red fluorophore. The red fluorescence of ASAP3-Kv provides a reference channel to remove motion artifacts from voltage-induced changes in green fluorescence. This allows for the visualization of membrane voltage changes throughout the cell cycle of motile cells . ASAP3-Kv surpasses existing sensors in reliably detecting single action potentials and tracking subthreshold potentials and high-frequency spike trains .
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| Papers (4) | Insight |
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| The paper does not mention ASAP3-KV. | |
| The paper does not mention "ASAP3-KV" specifically. The paper is about creating a high-performance ratiometric genetically encoded voltage indicator (GEVI) by fusing a voltage-independent red fluorescent protein (RFP) to ASAP3. | |
1 Citations | The provided paper does not mention anything about "asap3-kv" or "fluorescent voltage sensor." |
| The paper does not mention "asap3-kv" or any information related to it. The paper is about a mutated voltage-sensing domain and a fluorescent protein sensor for measuring action potential in neurons. |
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