Why males choose ICT strand rrl?
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Males may choose the ICT strand rrl due to specific mutations linked to male-biased diseases like Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) . In BPDCN, mutations in the X chromosome gene ZRSR2, encoding a splicing factor, are enriched in males, affecting pDC function and inflammatory responses, potentially altering immunity and predisposing to leukemic transformation. Additionally, advancements in RNA-dependent RNA polymerases (RDRs) could play a role in male preferences for ICT strands, as these enzymes are crucial for generating small interfering RNAs (siRNAs) in plants . Furthermore, the development of cotranscriptionally encoded RNA strand displacement (ctRSD) circuits offers a novel tool for molecular computation, potentially influencing male choices in ICT strands for various applications . These factors collectively contribute to the male selection of ICT strand rrl.
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