Showing papers on "Alkoxy group published in 1988"

Sol-gel kinetics I. Functional group kinetics☆

Abstract: 1 H and 29 Si NMR were used to measure the concentrations of the various functional groups (alkoxy, silanol and SiOSi bond) in an acid-catalyzed Si(OCH 3 ) 4 (TMOS):CH 3 OH:H 2 O sol-gel solution. There are three kinds of functional group reactions: hydrolysis, water producing condensation and alcohol producing condensation. The hydrolysis rate constant was found to be greater than 0.2 1/(mol min). The water-producing condensation and alcohol-producing condensation rate constants are 0.006 and 0.001 1/(mol min), respectively. The rate of hydrolysis is much faster than either rate of condensation. Both condensation pathways are significant for typical sol-gel reaction conditions.

Substituted 1,4,7-triscarboxymethyl-1,4,7,10-tetraazacyclo-dodecane and analogs

Abstract: Metal-chelating liquids having the formula ##STR1## wherein Y is oxygen or ##STR2## R 1 is hydrogen, alkyl, arylalkyl aryl, alkoxy, hydroxyalkyl ##STR3## wherein G is ##STR4##

Camptothecin derivatives and process for preparing same

Abstract: New Camptothecin derivatives possessing high anti-tumor activity with slight toxicity, represented by the general formula: ##STR1## wherein R 1 is a hydrogen atom, an alkyl group, a hydroxyl group, an alkoxy group or an acyloxy group, R 2 for a hydrogen atom, an alkyl group, an aralkyl group, a hydroxymethyl group, a carboxymethyl group or an acyloxymethyl group, and R 3 is the grouping --XR' (where R' is a hydrogen atom, an alkyl group or an acyl group and X is an oxygen atom or a sulfur atom), a nitro group, an amino group, an alkylamino group, an acylamino group or a halogen atom, with the proviso that when both of R 1 and R 2 are hydrogen atoms, R 3 should not be a hydroxyl group, methoxy group or acetoxy group. These new camptothecin derivatives are prepared by treating a 5-R 1 -7-R 2 -camptothecin derivative with a peroxidant and then reacting the resultant 5-R 1 -7-R 2 -camptothecin-1-oxide with an active hydrogen compound under irradiation of UV-rays or by catalytically hydrogenating the ring B of camptothecin in a solvent, treating the resultant tetrahydro product with an acylating agent, introducing a nitro group into the 10-position of the acylated product by the reaction with nitric acid, splitting off the acyl group in the 10-nitro product by hydrolysis and treating the hydrolyzed tetrahydro product with an oxidizing agent for dehydrogenation, and if desired, reducing the nitro group in the resulting product to an amino group and modifying the amino group by N-alkylation, N-acylation or by diazotization followed by hydrolysis or the Sandmeyer reaction, before or after the oxidation of the 10-nitro-tetrahydro product.

Octa-alkoxy phthalocyanine and naphthalocyanine derivatives: dyes with Q-band absorption in the far red or near infrared

Abstract: The lithium alkoxide-catalysed cyclic tetramerisation of various 3,6-dialkoxy-4,5-dichlorophthalonitriles, 1,4-dialkoxynaphthalene-2, 3-dicarbonitriles and 3,6-dialkoxyphthalonitriles to give the corresponding metal-free octa-alkoxyoctachlorophthalocyanines, octa-alkoxynaphthalocyanines and octa-alkoxyphthalocyanines is described. An unexpected trans-alkoxylation reaction occurs during the cyclisation of the first two series of precursors. Metal-free phthalocyanines and naphthalocyanines have been converted into derivatives containing various metal ions. Compounds show Q-band absorption in the region 739–862 nm in toluene solution. The fluorescence spectra of selected examples are reported. The solubility of some of the compounds has been measured in a formulation of liquid crystal materials.

Curable organopolysiloxane composition

Abstract: The addition-curable composition of the present invention, because it comprises a special component as component (D), is characterized by an excellent bonding to any of various substrates with which it is in contact during curing. Component (D) is a mixture, or reaction product, of (a) a silicon-free compound which contains at least 1 alcoholic hydroxyl group and at least 1 alkenyl group in each molecule, and (b) an organosilane having in each molecule at least 1 alkoxy group and at least 1 epoxy or methacryloxy or acryloxy group.

Aminopolycarboxylic acids and derivatives thereof

Abstract: There are provided chelating agents particularly useful for the preparations of diagnostic and therapeutic agents for magnetic resonance imaging, scintigraphy, ultrasound imaging, radiotherapy and heavy metal detoxification, said agents being compounds of formula X-CHR1-NZ-(CHR1)n-A-(CHR1)m-NZ-CHR1-X wherein (each of the groups Z is a group -CHR1X or the groups Z together are a group -(CHR1)q-A'-(CHR1)r-, where A' is an oxygen or sulphur atom or a group -N-Y; A is a group -N-Y or A-(CHR1)m- represents a carbon-nitrogen bond or, when the groups Z together are a group -(CHR1)q-A'-(CHR1)r-, A may also represent an oxygen or sulphur atom; each Y, which may be the same or different, is a group -(CHR1)p-N(CHR1X)2 or a group -CHR1X; each X, which may be the same or different, is a carboxyl group or a derivative thereof or a group R1; each R1, which may be the same or different, is a hydrogen atom, a hydroxyalkyl group or an optionally hydroxylated alkoxy or alkoxyalkyl group; n, m, p, q and r are each 2, 3 or 4; with the provisos that at least two nitrogens carry a -CHR1X moiety wherein X is a carboxyl group or a derivative thereof, that each -CHR1X moiety is other than a methyl group, and that unless A' is oxygen or sulphur or A is N-(CHR1)p-N(CHR1X)2 at least one R1 is other than hydrogen) and salts thereof.

Generation of alkoxy radicals from N-alkoxypyridinethiones

Abstract: L'ordre relatif de facilite de scission des groupes alcoxy est: cyclopentyloxy>>cyclohexyloxy>>t-butoxy

Chiral smectic C liquid crystals having an electronegative substituent ortho to the chiral tail group - a study of a factor determining the magnitude of spontaneous polarization

Abstract: Chiral smectic C compounds having an ester group in the central core, an optically active tail group (alkoxy or alkoxycarbonyl), and an electronegative substituent (halogen or cyano) ortho to the chiral tail were synthesized. The effect of the ortho substitution on the characteristics, especially on spontaneous polarization (Ps), was examined. When the chiral tail is a 1-methylheptyloxy group the lateral substituent increases Ps relative to the unsubstituted analogue. In the case of 1-methylheptyloxycarbonyl tail group, however, the lateral substituent decreases Ps relative to the unsubstituted. These effects of lateral substituents are explained in terms of chemical structure of a single molecule, i. e., by taking statistical weight of conformers and the associated electric dipole moments into account.

Tires made of silica filled, silane modified rubber

Abstract: There is a tire having tire performances such as wear resistance, cut resistance, heat build-up and the like and a processability simultaneously and economically improved by the application of a rubber composition containing a rubbery polymer modified with a silane compound and silica. The rubbery polymer modified with the silane compound is obtained by reacting an active terminal of a living polymer, which is obtained by polymerizing a monomer in the presence of an organic alkali metal catalyst, with a silane compound represented by the following general formula: X.sub.n Si(OR).sub.m R'.sub.4-m-n (where X is a halogen atom selected from a chlorine atom, a bromine atom and an iodine atom, OR is a non-hydrolyzable alkoxy group having a carbon number of 4˜20, an aryloxy group or a cycloalkoxy group, R' is an alkyl group having a carbon number of 1˜20, an aryl group, a vinyl group or a halogenated alkyl group, m is an integer of 1˜4, n is an integer of 0˜2, and a sum of n and m is 2˜4), which is contained in an amount of not less than 10% by weight as a rubber ingredient, and silica is contained in an amount of 5˜200 parts by weight based on 100 parts by weight of the rubber ingredient.

Synthesis of 4-substituted-3-alkoxy-3-cyclobutene-1,2-diones

Abstract: Les composes du titre sont prepares par addition d'organolithiens sur des dialcoxy-3,4 cyclobutene-3diones-1,2, suivie de l'addition d'anhydride trifluoroacetique

New amino acid derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same

Abstract: A compound of the formula : wherein R 1 is lower alkyl optionally substituted with a substituent selected from the group consisting of acyl,hydroxy, lower alkoxy, aryl, lower alkylthio and a group of the formula : in which R 5 is hydrogen or acyl and R 6 is hydrogen or lower alkyl; aryl; or amino optionally substituted with substituent(s) selected from the group consisting of lower alkyl and acyl; and R 2 is hydrogen or lower alkyl; or R 1 and R 2 are taken together with the attached nitrogen atom to form a heterocyclic group optionally substituted with substituent(s) selected from the group consisting of lower alkyl, hydroxy(lower)alkyl, lower alkoxy(lower)alkyl, acyl(lower)alkyl, oxo and acyl; R 3 is hydrogen or lower alkyl; and R 4 is lower alkyl; and its pharmaceutically acceptable salt, processes for the preparation thereof and pharmaceutical composition comprising the same.

Method for inhibiting hyperproliferative diseases

Abstract: A method of treating hyperproliferative skin diseases, such as psoriasis, using a compound of formula ##STR1## wherein R1 is hydrogen when R2 is hydroxy, and R1 is methyl when R2 is hydrogen; and A is alkyl; cycloalkyl; alkenyl; alkyl substituted with trifluoromethyl; phenyl; halophenyl; phenyl-C1-3 alkyl; phenyl-C1-3 alkyl substituted on the phenyl with 1 to 3 substituents selected from the group consisting of halo, C1-3 alkyl, and C1-3 alkoxy; or A is ##STR2## wherein R3 is hydrogen or ##STR3## R4 is hydrogen or methyl, and n is 1 to 5, or the corresponding hydroxy acid of formula ##STR4## or a pharmaceutically acceptable salt of said acid, an alkyl ester of said acid, an acetylamino-substituted-C1-4 alkyl ester of said acid, a phenyl-dimethylamino ester of said acid or a α-monoglyceride of said acid.

Oxime ethers and fungicides containing these compounds

Abstract: Oxime ethers of the formula ##STR1## where R1 and R2 are hydrogen or alkyl, X(m=1 to 5) is halogen, cyano, trifluoromethyl, nitro, alkyl, alkoxy, unsubstituted or substituted phenyl, unsubstituted or substituted phenoxy, unsubstituted or substituted benzyloxy or hydrogen, and Y is methyleneoxy, oxymethylene, ethylene, ethynylene or oxygen, and fungicides containing these compounds

Ink jet recording process using certain benzotriazole derivatives as light stabilizers

Abstract: UV-absorbers of the formula I ##STR1## in which n is 1 to 4, R is H, C1 -C12 alkyl, C5 -C8 cycloalkyl, phenyl or C7 -C9 phenylalkyl, R1 is H, Cl, C1 -C4 alkyl or C1 -C4 alkoxy and R2 is an n-valent hydrophilic group, are especially suitable for the light stabilization of ink-jet prints. The compound of the formula I is here added to the recording material, preferably in a surface coating. Such compounds have the further advantage that they form particularly stable emulsions.

Pyrimidine derivatives, processes for their production, and herbicidal method and compositions

Abstract: A pyrimidine derivative having the formula: ##STR1## wherein R is hydrogen atom, --CH2 CH2 S(O)n R1 (wherein R1 is a lower alkyl group, and n is an integer of from 0 to 2) or ##STR2## (wherein each R1 is a lower alkyl group), A is a chlorine atom or a methoxy group, and each of D and E which may be the same or different, is a hydrogen atom, a halogen atom, a lower alkyl group, a lower alkoxy group or a halogen-substituted lower alkoxy group, or a salt thereof.

Process for improving the photochemical stability of dyeings on polyester fibre materials

Abstract: A process is described for improving the photochemical stability of dyeings on polyester fibre materials by means of UV absorbers of the formula ##STR1## in which R is lower alkyl, lower alkoxy, halogen or hydroxyl, R 1 and R 2 independently of one another alkyl which is substituted by hydroxyl, lower alkoxy, lower alkylthio, amino, monoalkylamino or dialkylamino, phenyl, phenyl which is substituted by chlorine, lower alkyl or lower alkoxy, or o-hydroxyphenyl, and n is 0, 1 or 2.

Composition for controlling parasites in productive livestock

Abstract: Novel 13-spiro-2'-[tetrahydrofuran]-milbemycins of the formula I ##STR1## in which X represents one of the groups --CH(OR 1 )--, --C(═O)-- or --C(═N--OH)--; R 1 represents hydrogen or a OH-protecting group; R 2 represents methyl, ethyl, isopropyl or sec.-butyl or the group --C(CH 3 )═CH--A in which A represents methyl, ethyl or isopropyl; and R 3 represents hydrogen; C 1 -C 10 -alkyl; C 1 -C 10 -alkyl substituted by at least one substituent selected from the group consisting of halogen, C 1 -C 6 -alkoxy, C 2 -C 6 -alkoxyalkoxy, C 3 -C 9 -alkoxyalkoxyalkoxy, C 1 -C 6 -alkylthio, C 3 -C 7 -cycloalkyl, C 1 -C 3 -alkyl-substituted C 3 -C 7 -cycloalkyl, hydroxy, benzyloxy, C 1 -C 6 -acyl and C 1 -C 6 -acyloxy, it being possible for each of the above-mentioned radicals representing or containing an alkoxy group to be terminally substituted at a terminal alkoxy group by hydroxy, halogen, C 1 -C 6 -acyl or by C 1 -C 6 -acyloxy; C 3 -C 7 -cycloalkyl; C 3 -C 7 -cycloalkyl substituted by at least one substituent selected from the group consisting of halogen and C 1 -C 3 -alkyl; C 3 -C 7 -cycloalkenyl; C 2 -C 10 -alkenyl; C 2 -C 10 -alkynyl; a radical selected from the group consisting of C 2 -C 10 -alkenyl and C 2 -C 10 -alkynyl, which radical is substituted by halogen, C 1 -C 6 -alkoxy or by C 1 -C 6 -acyloxy; 1-adamantylmethyl; menthyl; carveyl; phenyl; benzyl; naphthyl; a radical selected from the group consisting of phenyl, benzyl and naphthyl, which radical is substituted by at least one substituent selected from the group consisting of halogen, C 1 -C 3 -alkyl, C 1 -C 3 -haloalkyl, C 1 -C 3 -alkoxy, C 1 -C 3 -haloalkoxy, C 1 -C 3 -alkylthio, nitro and cyano; benzyl substituted by a phenoxy group; or a four- to six-membered heterocyclic radical that has from one to three hetero atoms selected from the group consisting of oxygen, sulfur and nitrogen and that is unsubstituted or is substituted by at least one substituent selected from the group consisting of halogen, C 1 -C 3 -alkyl, C 1 -C 3 -haloalkyl, C 1 -C 3 -alkoxy, C 1 -C 3 -haloalkoxy, C 1 -C 3 -alkylthio, nitro and cyano, it being possible for the said heterocyclic radical also to be bonded via a C 1 -C 6 -alkylene bridge to the oxygen atom in the 5'-position of the tetrahydrofuran ring, their preparation and their use against parasites in productive livestock and against insect pests, are described.

Insecticides and parasiticides

Abstract: The present invention relates to novel C(29)-oximinomilbemycin derivatives of formula I, to their preparation and to the use thereof for controlling pests. The invention further relates to pesticidal compositions which contain at least one of these compounds as active ingredient. The novel compounds have the general formula I ##STR1## wherein X is a group selected from --CH(OR 1 )--, --C(O)-- or --C(═N--OR)--, R 1 is hydrogen or a OH protective group, R is hydrogen, a OH protective group, an alkyl, cycloalkyl or acyl group, R 2 is methyl, ethyl, isopropyl, sec-butyl or the ##STR2## wherein A is methyl, ethyl or isopropyl; and R 3 is hydrogen, C 1 -C 6 alkyl, C 2 -C 6 alkenyl, a radial selected from the group consisting of phenyl and benzyl which is unsubstituted or substituted by one or more members selected from the group consisting of halogen, C 1 -C 3 alkyl, C 1 -C 3 alkoxy, C 1 -C 3 alkylthio, C 1 -C 3 haloalkyl, nitro or cyano, or is the group U ##STR3## wherein n is 0, 1, 2, 3, 4 or 5, E is oxygen or --CH(R d )-- and R z is hydrogen, R a is hydrogen, halogen, C 1 -C 3 alkyl, C 1 -C 3 alkoxy or 2-tetrahydropyranyl, and R b , R c and R d are each independently hydrogen, halogen, C 1 -C 3 alkyl or C 1 -C 3 alkoxy, which group U may also be in unsaturated form.

Water soluble disazo compounds, process for their preparation and their use as dyestuffs

Abstract: 1. Disazo compounds of the general formula (1) see diagramm : EP0133283,P11,F1 in which D is the phenyl radical or a naphthyl radical, both of which can be substituted by a sulfo group of the formula -SO3 M and furthermore by one or two substituents from the group comprising methyl, ethyl, methoxy, ethoxy, chlorine, bromine and carboxy of the general formula -COOM, and each of which is substituted by one or two groups of the general formula -SO2 -X, in which X represents the vinyl group or a beta-sulfatoethyl group of the general formula -CH2 -CH2 -OSO2 M ; M is a hydrogen atom or an alkali metal ; R is the acyl radical of an aliphatic or aromatic carboxylic acid or of an aliphatic or aromatic sulfonic acid or a radical of the formula (2a) see diagramm : EP0133283,P11,F3 in which R*** is a sulfophenylamino group, the beta-sulfoethylamino group or the N-methyl-beta-sulfoethylamino group, and R**+ represents the hydroxy, methoxy, ethoxy, amino or methylamino group.

Control of the Discotic to Isotropic Transition in Alkoxy-Substituted Silicondihydroxo-Phthalocyanines by Axial Substituents

Abstract: The synthesis of a homologous series of octaalkoxy-substituted silicondihydroxo-phthalocyanines is described. The mesomorphic properties of these new materials were studied by DSC, optical microscopy and X-ray investigations. Compounds with n ≤ 4 (n is the number of carbon atoms in a single alkoxy side chain) show a discotic mesophase transition. A transition to the isotropic state is only observed when n ≤ 8. X-ray diffraction patterns of the mesophases confirm that all compounds form a hexagonal columnar mesophase of the type Dhd.

substituted aralkyl) heterocyclic compounds

Abstract: A (substituted-aralkyl)heterocyclic compound of the formula I ##STR1## wherein R 1 is an azido, carbamoyl, cyano, formyl, hydroxy or nitro radical, a 1-6C 1-hydroxyalkyl, alkoxy, alkylcarbamoyl, alkylthio, alkylsulphinyl or alkylsulphonyl radical, a 2-cyanoethyl radical, optionally bearing one to four 1-6C alkyl substituents, or a 2-6C alkanoyl, halogenoalkanoyl, alkanoyloxy, alkanoylamino, dialkylcarbamoyl or alkoxycarbonyl radical; R 2 and R 3 , which may be the same or different, are each a hydrogen atom, a 1-6C alkyl, dueterioalkyl or halogenoalkyl radical, or a phenyl or phenyl(1-6C alkyl) radical, in each of which the phenyl may optionally bear one or more substituents; or R 2 and R 3 , together with the carbon atom to which they are attached, may form a 3- to 6-membered ring; or R 1 R 2 R 3 C- is a 1,1-dicyanoethyl or trifluoromethylsulphonyl radical; R 4 is a hydrogen or halogen atom, a cyano or nitro radical or a 1-6C alkyl or halogenoalkyl radical; R 5 has any of the values defined above for the group R 1 R 2 R 3 C but is not necessarily the same as R 1 R 2 R 3 C, or has any of the values defined above for R 4 but is not necesarily the same as R 4 , or is a carbamoyl, 1-pyrrolidinyl-carbonyl, piperidinocarbonyl, morpholinocarbonyl or nitro radical, a 1-6C alkoxy or halogenoalkoxy radical or a 2-6C alkanoyl or alkoxy-carbonyl radical; A is a methylene or ethylene radical optionally bearing one or more substituents selected from deuterium and halogen atoms, carbamoyl, cyano and hydroxy radicals, 1-6C alkyl and alkoxy radicals, and 2-6C alkanoyloxy radicals provided that when A is linked to R 6 through a nitrogen atom thereof, it may not bear a hydroxy, alkoxy or alkanoyloxy substituent on the carbon atom adjacent to such nitrogen atoms; and R 6 is a 1H-1,2,4-triazol-1-yl, 4H-1,2,4-triazol-4-yl, 1H-imidazol-1-yl, 5-cyano-1H-imidazol-1-yl, 3-pyridyl or 5-pyrimidinyl radical, or a 1H-imidazol-1-yl radical, bearing at the 5-position thereof a 1-6C alkyl substituent which is itself optionally substituted by one or more carbamoyl, cyano, hydroxy or 2-6C alkoxycarbonyl radicals; and provided that when R 2 , R 3 , R 4 and R 5 are hydrogen, A is a methylene radical and R 6 is a 3-pyridyl radical, R 1 is not a cyano, hydroxy or hydroxymethyl radical, and when R 1 is a hydroxy radical, R 3 , R 4 and R 5 are hydrogen, A is a methylene radical and R 6 is 3-pyridyl, R 2 is not a methyl or a 2-chloro-1-methylethyl radical, and provided that when R 1 is a methoxycarbonyl radical, R 2 , R 3 , R 4 and R 5 are hydrogen and A is a methylene radical, R 1 is not a 1H-imidazol-1-yl radical; and the pharmaceutically acceptable acid addition salts thereof.