Showing papers on "Aryl radical published in 1991"

Electron paramagnetic resonance spin trapping detection of short-lived radical intermediates in the direct photolysis of 4-chlorophenol in aerated aqueous solution

Abstract: The photolysis of 4-chlorophenol (I) in aqueous solution (pH 6.5–10.5) in the presence of the spin trap 5,5-dimethylpyrroline-N-oxide (DMPO) results in the formation of at least five distinct electron paramagnetic resonance (EPR) spectra. We identified three of these as arising from the DMPO spin adducts of the hydrogen atom (or a hydrated electron plus later protonation) (spectrum A), an aryl radical (probably the p-hydroxyphenyl radical) (spectrum B) and the ·OH radical (spectrum C). Spectrum D probably arises from a decomposition product of one or more of the spin adducts, and spectrum E is that of the p-benzosemiquinone anion. By examining EPR spectra after various lengths of UV irradiation, and determining the time course of the growth of each spectrum, we established that spectra A and B appear immediately on initiation of the photolysis. In contrast, the growth of spectrum C is sigmoidal, indicating that it arises from a secondary product. We present a mechanism, based on primary radicals detected, that accounts for the photoconversion of I to p-benzoquinine (II).

Softening compositions including quaternary ammonium functional siloxanes

Abstract: A fabric softener including a silicon compound having the formula [(R.sub.3 SiO).sub.2 --SiR--(CH.sub.2).sub.a ].sub.b N.sup.+ R'.sub.4-b X - wherein R is an alkyl radical having one to six carbon atoms; R' is an alkyl or aryl radical having one to eighteen carbon atoms; X is chloride, bromide, iodide, nitrate, or RSO 4 - ; a is an integer having a value from one to ten; and b is an integer having a value of two or three.

Aminopiperidine indanyl and benzocyclobutene compounds

Abstract: The invention relates to new compounds of formula I: ##STR1## in which: m represents zero, 1, 2, 3 or 4, n and p represent zero, 1 or 2, W represents an oxygen atom, an --NH-- radical, or a single bond, R represents a benzocyclobuten-1-yl radical, or an indanyl radical, a 2,3-dihydrobenzofuran-2-yl R1 represents a hydrogen atom, an alkyl radical having from 1 to 6 carbon atoms, or an aryl radical, and R2 represents a hydrogen atom, an alkyl radical, an alkenyl radical, a cycloalkyl radical, a benzyl radical, a phenyl radical, an aralkyl radical, an alkoxyalkyl radical or a polyhalogenated alkyl radical, the optical isomers thereof and the addition salts thereof with a pharmaceutically acceptable organic or mineral acid, and medicaments containing the same.

Paints and use of these paints as topcoats for the finishing of automobile bodies

Abstract: The invention relates to paints which contain a compound of the general formula (I) or a mixture of compounds of the general formula (I), the general formula (I) being ##STR1## and n, m, X, R1, R2, R3, R4, R5 and Y having the following meaning: - n stands for a number between 2 and 25, preferably for a number between 5 and 15 - m stands for a number from 0 to 5 - X and Y can be identical or different and stand for a functional group, for example a hydroxyl, amino, carboxyl or NCO group - R1 and R4 can be identical or different and stand for an alkylene radical, preferably for an alkylene radical having 1 to 6 carbon atoms, or for an arylene radical, preferably a phenylene radical - R2 and R3 can be identical or different and stand for an alkyl radical, preferably for an alkyl radical having 1 to 3 carbon atoms, or for an aryl radical, preferably for a phenyl radical - R5 stands for ##STR2## Z standing for X, Y or R2. Compounds of the general formula (I) improve especially the acid, brush and weather resistances and the water-repellent characteristics of the paint films prepared using these paints.

Substituted sulfonamides, processes for their preparation and medicines containing them

Abstract: New substituted sulphonamides, their salts, complexes, esters and amides which are physiologically acceptable, denoted by the formula in which: R1 is an aryl radical or a heterocyclic ring, optionally (poly)substituted; R2 and R3 are different; one of the two denotes W, the other is hydrogen, halogen, trifluoromethyl, alkyl, cycloalkyl, alkoxy, alkylthio, alkylsulphinyl, alkylsulphonyl, acyl, thioacyl, hydroxyl, optionally (poly)substituted amine, nitro, nitrile, azide or aryl; W is a -Z-Ar-(CH2)q-A group in which A is CO2H or a group capable of being hydrolysed to CO2H, SO3H, PO3H, a heterocyclic ring, an acyl radical, an oxoalkylcarboxylic radical or a primary alcohol; q is 0,1,2,3 or 4; Ar is an aryl radical or an aromatic heterocyclic ring, optionally substituted by a radical R7; Z is oxygen, CH2 or a bond; R4-7 take simultaneously or independently the values of R2-3, except W; Y is a -(CH2)s-B-(CH2)t- group; s and t are 0,1 or 2; B is an oxygen atom, oxidised or unoxidised sulphur, optionally substituted nitrogen, a (thio)carbonyl functional group, a heterocyclic ring, an alkylene radical, an optionally substituted alkyl radical or a bond; n is 0 or 1. Application of these thromboxane A2 receptor antagonist compounds with a long period of activity as antithrombotic and antiasthmatic medications.

Compounds for the combat against plant diseases

Abstract: Halothiophenecarboxylic acid derivatives of the formula in which Hal is chlorine or bromine, n is the number 2 or 3, , in the event that the radicals R and R differ from each other, is either an enantiomer or a racemate, R is hydrogen or an alkyl radical, R is hydrogen, an alkyl radical which can optionally be substituted by hydroxyl, carboxyl, alkoxy or alkoxycarbonyl, mercapto or alkylmercapto or benzylmercapto, an aryl radical or aralkyl radical, it being possible for the ring system to be optionally substituted by fluorine, chlorine or bromine atoms, or is a cycloalkyl radical or cycloalkylmethyl radical, R is hydrogen, an alkyl radical, alkenyl or alkynyl radical, or, if appropriate, R and R or R and R together can form an alkylene bridge in which a CH2 unit can optionally be substituted by NR1, O or S, Y is OH, OR4 or NR5R6, where R is an alkyl radical where all or some of the hydrogen atoms may be replaced by halogen atoms, R is hydrogen, an alkyl radical, hydroxyl radical or alkoxy radical, R is hydrogen, an alkyl radical, a phenyl radical or a cycloalkyl radical, or, if appropriate, R and R can form a ring including the nitrogen atom and, if appropriate, a further hetero atom. There is furthermore described a process for their preparation. Compounds of the formula I can be used together with suitable carrier materials, in the form of crop protection agents.

Novel aminopiperidine, aminopyrrolidine and aminoperhydroazepine derivatives, process for their preparation and pharmaceutical compositions containing them

Abstract: L'invention concerne des nouveaux composes de formule I : The invention relates to novel compounds of formula I: dans laquelle : in which : - m represente zero, 1, 2, 3 ou 4, - m represents zero, 1, 2, 3 or 4, - n et p representent zero, 1 ou 2, - n and p represent zero, 1 or 2, - W represente un atome d'oxygene, un radical -NH-, ou est une simple liaison, - W represents an oxygen atom or a -NH- radical, or is a single bond, - R represente un radical 1,2-dihydro 2-oxo 1-phenyl 1,8-naphthyridin-3-yle, un radical benzocyclo- buten-1-yle, un radical indanyle, un radical 2,3-dihydro benzofuran-2-yle ou un radical 4-oxo 4H-chromen-2-yle, - R represents a 1,2-dihydro-2-oxo 1-phenyl-1,8-naphthyridin-3-yl, radical benzocyclo- buten-1-yl, indanyl radical, a 2,3-dihydro benzofuran-2 yl radical or a 4-oxo-4H-chromen-2-yl, - R 1 represente un atome d'hydrogene, un radical alkyle de 1 a 6 atomes de carbone ou un radical aryle, et - R 1 represents a hydrogen atom, an alkyl radical of 1 to 6 carbon atoms or an aryl radical, and - R 2 represente un atome d'hydrogene, un radical alkyle, un radical alcene, un radical cydoalkyle, un radical benzyle ou un radical phenyle, un radical aralkyle, un radical alcoxyalkyle ou un radical alkyle polyhalogene ; - R 2 represents a hydrogen atom, an alkyl radical, an alkene radical, a cydoalkyle, benzyl or phenyl radical, an aralkyl radical, an alkoxyalkyl radical or a polyhalogenated alkyl radical; leurs isomeres optiques et leurs sels d'addition avec un acide organique ou mineral pharmaceutiquement acceptable. their optical isomers and addition salts thereof with a pharmaceutically acceptable organic or mineral acid. Medicaments pharmaceuticals

Optically active alpha -amino aldehydes, process for the preparation thereof, and the use thereof for the stereoselective preparation of optically active beta -amino alcohols

Abstract: The invention relates to new optically active alpha -amino aldehydes of the formulae I in which R1 represents an optionally substituted alkyl, alkenyl, aralkyl or aryl radical, and R2 and R3, independently of one another, denote an optionally substituted alkyl, alkenyl, cycloalkyl or aralkyl group, together form an optionally substituted phenylene-(1,2)-bis-methylene radical, or R2 is an optionally substituted, alkyl, cycloalkyl or aralkyl radical, and R3 forms together with R1 a 1,3-propylene radical. a process for the preparation thereof, and the use thereof for the stereoselective preparation of optically active beta -amino alcohols.

Living polymers, the preparation thereof and the use thereof for preparing telechelic polymers

Abstract: A process for preparing bifunctional living polymers which are able to forth bifunctional telechelic polymers or block copolymers with at least 3 blocks of conjugated dienes and/or vinylaromatics with molecular weights of from 1,500 to 500,000, by bifunctional initiators whose anionic centers are aliphatic carbon atoms which are substituted by lithium and an aliphatic hydrocarbon radical as well as by either 2 aryl radicals or by one aryl radical and one hydrogen radical, where one of the aryl radicals can also be part of the two anionic centers, in a first stage being reacted in the presence of not more than 2.5 moles of an aliphatic ether or a tertiary amine per mole of lithium and not less than 2 mol/l of a conjugated diene at from -40° to +35° C. with not less than two moles of diene, resulting in the formation of low molecular weight diene oligomers which in turn act as bifunctional initiators, and using the latter in a second reaction stage in a conventional manner at above 40° C., with or without the addition of other monomers, to obtain polymers of the required molecular weight.

Process for the preparation of a melanic pigment by an enzyme route and its use in cosmetics

Abstract: The invention relates to a process for the preparation of a melanic pigment, comprising the polymerisation of a compound corresponding to the formula: ##STR1## in which: R denotes a hydrogen atom, an alkyl, alkoxy, hydroxyalkyl, SiR 4 R 5 R 6 or aminoalkyl radical, or an aryl radical which is unsubstituted or substituted by OH, NH 2 , alkyl, alkoxy or NO 2 ; R 1 and R 2 denote alkyl groups or together form a methylene or ethylene group which is optionally substituted by one or more alkyl groups, and R 2 denotes hydrogen or COOH, in the presence of an oxidizing medium and of an enzyme with (per)oxidizing activity or of a compound which has a similar activity, and to powders which make use of them and to their cosmetic use.

Derivatives of benzimidazole and their use as antihistamines

Abstract: The present invention relates to novel compounds derived from benzimidazole, characterized in that they correspond to the formula I, or their therapeutically acceptable salts, ##STR1## in which: R 1 and R 2 , equal or different, represent a hydrogen atom, a halogen, a lower alkyl radical, a hydroxy radical, an alkoxy radical, an alkyl carboxylate radical, an aryl or substituted aryl radical, n may have the values 0 or 1, m may have the values 2 to 4, X, Y, Z and W, equal or different, represents a nitrogen atom or a carbon atom bonded to a hydrogen atom, a halogen or another alkyl, aryl, alkoxycarbonyl, carboxy, hydroxyl, sulfonic and alkylsulfonic radical. The present invention relates also to the treatment of various allergic disorders caused by histamine.

Azo dyes and the production and use thereof

Abstract: The present invention relates to azo dyes of the formula ##STR1## wherein X is an aryloxy radical or an unsubstituted or substituted C 1 -C 12 alkyl radical, a cycloalkyl radical or an aryl radical or a group of the formula ##STR2## wherein R 1 is hydrogen, unsubstituted or substituted lower alkyl, cycloalkyl or aryl, and R 2 is hydrogen or unsubstituted or substituted lower alkyl, or wherein R 1 and R 2 , together with the nitrogen atom to which they are attached, form a 5- or 6-membered heterocyclic ring which may contain a further hetero-atom, Y is halogen, low molecular alkyl or low molecular alkoxy, and K is the radical of a coupling component of the benzene or naphthalene series or of the heterocyclic series. These dyes yield dyeings of good light- and wetfastness on polyamide material.

Gas-phase rearrangement and cyclisation reactions of 2-benzylphenylaminyl radicals and related 2-hetero-analogues

Abstract: Gas-phase pyrolysis of the appropriate N-allyl or N-benzyl compound leads to the aminyl radicals 1(X = NH, Y = CH2, CO, S, or O). Equilibration of these via the spirodienyl 2 gives mixtures of isomeric acridans or acridones as major products from radicals 1(X = NH, Y = CH2 and Y = CO, respectively) and isomeric phenothiazines as minor products from radical 1(X = NH, Y = S). The major product in this case is the aminodibenzofuran 29 which may be formed by H-abstraction by the aminyl to give an aryl radical, followed by cyclisation (Scheme 6). The only cyclised product from radical 1(X = NH, Y = O) is the carbazole 35, formed by a mechanism similar to that of Scheme 6, but in which H-abstraction by the rearranged phenoxyl radical has taken place.

Benzimidazole derivatives, their preparation and their application as medicaments

Abstract: The invention relates to new compounds derived from benzimidazole, characterised in that they correspond to the general formula I, and to their therapeutically acceptable salts, in which: - R1 and R2, which may be the same or different, represent a hydrogen atom, a halogen, a lower alkyl radical, a hydroxyl radical, an alkoxy radical, an alkyl carboxylate radical, an aryl or substituted aryl radical, - n can have the values 0 or 1, - m can have the values 2 to 4, - X, Y, Z and W, which may be the same or different, and even forming part of another aromatic or non-aromatic ring, represent a nitrogen atom or a carbon atom linked to a hydrogen atom, a halogen or to another alkyl, aryl, carboxyalkyl, carboxyl, hydroxyl, alkylhydroxy, sulphonic and alkylsulphonic radical. The invention also relates to the process for preparing the compounds and to their use for the manufacture of medicaments intended for the prophylaxis and treatment of various histamine-induced allergic diseases.

Oxadiazole compounds containing 4,6-bis-trichloromethyl-S-triazin-2-yl groups, process for their preparation

Abstract: Compounds of general formula I are disclosed ##STR1## wherein R 1 denotes an unsubstituted or substituted carbocyclic or heterocyclic aryl radical, R 2 and R 3 are different from each other and either denote a hydrogen atom or a 4,6-bis-trichloromethyl-s-triazin-2-yl group, and n and m independently of each other, denote one of the numbers 0 and 1. The compounds are effective free-radical-forming photoinitiators and photolytically-activatable acid donors for photosensitive compositions.

Ammonium aryl hydrazide compounds

Abstract: Photographic silver halide elements containing aryl hydrazides as defined for the production of images with ultrahigh contrast and a new class of aryl hydrazides with a cationic group in the aryl radical as defined. The photographic silver halide elements can be developed at relatively low pH values and have low fog and low tendency to form black spots in unexposed or slightly exposed areas.

Aniline derivatives useful as color formers

Abstract: The present invention is concerned with aniline derivatives of the general formula: ##STR1## wherein R 1 is hydrogen or a lower alkyl or aryl, R 2 is hydrogen or a lower alkyl which can be substituted by hydroxyl, amino carboxyl, lower alkoxycarbonyl, lower alkanoylamide lower alkyl or aryl or by a group of the structure ##STR2## is which R 5 and R 6 have the meanings given hereinafter, R 3 is a hydrogen or halogen atom or a carboxyl group, R 4 and R' 4 , which can be the same or different, are hydrogen or halogen, carboxyl or lower alkoxy or lower alkyl radicals which are preferably in the m-position, R 5 is hydrogen or a lower alkyl and R 6 is hydroxyl or a lower alkoxy, lower alkyl or aryl radical; and of the salts thereof with acids and bases useful as a color former in the Trinder reaction for the detection of hydrogen peroxide or hydrogen peroxide-forming systems or peroxidase or peroxidate-acting substances or together with an oxidation agent for the detection of aromatic amines or of systems forming such amines.

Optical spectroscopy of the aryl cation Part 2. Matrix effects on the production of 3Ar

Abstract: Low-temperature UV and visible light photolyses of the diazonium salt 2,5-di- n -butoxy-4-morpholinobenzenediazonium tetrafluoroborate yield intermediates whose nature depends on the matrix, as determined by optical and electron spin resonance spectroscopy. The corresponding aryl radical and aryl cation are produced in various ratios in different matrices. Thus the aryl radical appears as the sole species in hydrocarbon matrices, and the aryl cation is observed as the only species in a sulphuric acid matrix. The λ max value of the absorption band of the aryl cation is located at 465 nm and is independent of the matrix. The aryl radical absorption occurs over the range 308–320 nm depending on the matrix, which reflects a distinct change in the dipole moment on going from a more polar state to a less polar state.

Derivatives of 1-diphenylmethyl piperazine and their use as antihistamines

Abstract: The present invention relates to novel derivatives of 1-diphenylmethyl piperazinyl, characterized in that they correspond to the general formula I, and their therapeutically acceptable salts, ##STR1## in which: R1 and R2, equal or different, represent a hydrogen atom, a halogen, a lower alkyl radical, a hydroxy radical, an alkoxy radical, an alkyl carboxylate radical, an aryl or substituted aryl radical, n may have the values 2 to 4, X, Y, Z and W, equal or different, represent a nitrogen atom or a carbon atom linked to a hydrogen atom, a halogen or to another alkyl, aryl, carboxyalkyl, carbonyl, hydroxyl, sulfonyl and alkylsulfonyl radical. The present invention also relates to the process of preparing these compounds and their use for the manufacture of medicaments intended for prophylaxis and for the treatment of various allergic disorders caused by histamine.

Sulfonamides of phenylalkylamines or phenoxyalkylamines processes for their preparation and medicaments containing these compounds

Abstract: Compounds of the formula I ##STR1## in which R1 signifies an aryl, aralkyl or an aralkenyl group, the aryl radical of which can, in each case, be substituted one or more times by halogen, cyano, alkyl, trifluoromethyl, alkoxy, alkylthio, trifluoromethoxy, hydroxyl or carboxyl, m a whole number from 1 to 3, n a whole number from 1 to 5, R2 hydrogen, an alkyl, aralkyl or acyl group, Q a bond or an oxygen atom, R3 hydrogen or a lower alkyl radical which is possibly terminally substituted by carboxyl or by a hydroxyl group and R4 hydrogen, a lower alkyl group with 1-4 C-atoms, which is possibly terminally substituted by carboxyl or hydroxyl, a possibly substituted phenyl, heteroaryl, cycloalkyl or acyl group or a group ##STR2## in which R5 represents a straight-chained or branched alkyl chain with 1-4 C-atoms which is possibly terminally substituted by carboxyl, alkoxycarbonyl, aminocarbonyl, hydroxyl, mercapto, alkylthio or imidazolyl and Y a carboxyl, an alkoxycarbonyl, aminocarbonyl or cyano, formyl, hydroxymethyl, aminomethyl or ortho ester group, whereby R3 and R4 can also be component of a 5- or 6-membered saturated or unsaturated possibly substituted heterocycle with 1-4 heteroatoms which can be annellated with further ring compounds via one or more bonds, as well as their salts, esters and amides, processes for their preparation and medicaments with thromboxane-antagonistic action which contain these compounds.

Copolyesters of terephthalic acid and 1,4-cyclohexanedimethanol having improved melt stability

Abstract: Disclosed are copolyesters of terephthalic acid and 1,4-cyclohexanedimethanol containing selected phosphites or phosphonites which improve molecular weight retention after exposure to melt temperatures. In the phosphite or phosphonite, at least one of the P-O bonds is attached to an aryl radical. The compositions are useful in clear injection molding applications.

A highly regioselective 6-endo-aryl radical cyclisation: stereocontrolled synthesis of trans-octahydroanthracenes

Abstract: The sterocontrolled synthesis of trans-octahydroanthracenes 3, 11 and 14 through implementation of an efficient and highly regioselective 6-endo-trig-aryl radical cyclisation of the respective 2-(o-bromobenzyl)-1-methylenecyclohexanes 2, 10 and 13, with tri-n-butyltin hydride is reported, along with a single crystal X-ray structure determination of 11.

Anisotropic polymers based on an S-triazine derivative.

Abstract: The invention relates to an aromatic polymer processable from the melt and showing anisotropic behaviour, which polymer contains a triazine unit according to formula I: where Y1 and Y2 are the same or different and comprise an (alkyl)carboxy, an (alkyl)hydroxy or an amino group, where R = hydrogen, alkyl radical with 1-4 C atoms, cycloalkyl radical with 3-6 C atoms, allyl radical, aryl radical or halogen, and m = 1 or 2; n = 0 or 1, if n = 1 then: X = -O-, -SO2- or -N=; or (X)n-(R)m is a group according to any one of formulas II: The polymer according to the invention has, in addition to a good thermal shock resistance, excellent mechanical properties and will mainly be used in the electrical engineering, the aircraft industry, the automative industry and for the production of ovenware.

Polymerized quaternary diallylammonium compounds

Abstract: The product of the polymerisation of a quaternary ammonium compound of the formula in which R is C1-C3-alkyl and Q is a C1-C3-alkylsulphate ion or the anion of an aromatic sulphonic acid, is prepared by reacting 1-diallylamino-2,3-epoxypropane with an alkyl sulphonate of the formula (2) Z-SO2-OR in which Z is an aryl radical or -OR, and R is as defined above, and polymerising the resultant quaternary ammonium compound of the formula (I). The polymerisation product contains virtually no dihalopropanol, such as dichloropropanol, and is particularly suitable as a retention aid or wet strength agent in papermaking and in particular for the aftertreatment of dyed cellulose fibre material.

Tin (iv) compounds

Abstract: Novel tetracoordinated tin (IV) compounds, well suited as latent catalysts for the preparation of polyurethanes or for the crosslinking of curable diorganopolysiloxanes (upon thermal decomposition thereof into diorganotin dicarboxylates or dialcoholates), have the general formula (1): ##STR1## in which the radicals R, which may be the same or different, are each a linear or branched chain C1 -C20 alkyl radical, a mononuclear aryl radical, or an aralkyl or alkaryl radical, the alkyl moieties of which having from 1 to 6 carbon atoms; the radicals R1 and R2, which may be the same or different, are each a hydrogen atom, a cyano radical, a C1 -C6 alkyl radical, or an alkoxycarbonyl radical, the alkyl moiety of which having from 1 to 6 carbon atoms, with the proviso that R1 and R2 may together form a saturated hydrocarbon ring member having from 5 to 8 carbon atoms; the radical R3 is a hydrogen atom, a linear or branched chain C1 -C20 alkyl radical, a linear or branched chain C1 -C20 alkoxy radical, a mononuclear aryl radical or a mononuclear aryloxy radical; and a is 0 or 1.