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A. L. Mibus
Researcher at University of Melbourne
Publications - 4
Citations - 426
A. L. Mibus is an academic researcher from University of Melbourne. The author has contributed to research in topics: Offspring & Litter (animal). The author has an hindex of 3, co-authored 4 publications receiving 403 citations.
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Journal ArticleDOI
Normal Lactational Environment Restores Nephron Endowment and Prevents Hypertension after Placental Restriction in the Rat
TL;DR: It is shown for the first time that a prenatally induced nephron deficit can be restored by correcting growth restriction during lactation and the prenatal and postnatal nutritional environments in the programming of adult hypertension, associated with distinct renal changes are identified.
Journal ArticleDOI
Uteroplacental insufficiency causes a nephron deficit, modest renal insufficiency but no hypertension with ageing in female rats
Karen M. Moritz,Marc Q. Mazzuca,Andrew L. Siebel,A. L. Mibus,D. Arena,Marianne Tare,Julie A. Owens,Mary E. Wlodek +7 more
TL;DR: Growth, blood pressure and nephron endowment in female offspring from mothers which underwent bilateral uterine vessel ligation on day 18 of pregnancy were examined, suggesting that perinatally growth restricted female offspring may be susceptible to onset of renal injury and renal insufficiency with ageing in the absence of concomitant hypertension.
Journal ArticleDOI
Improved lactational nutrition and postnatal growth ameliorates impairment of glucose tolerance by uteroplacental insufficiency in male rat offspring.
Andrew L. Siebel,A. L. Mibus,Miles J. De Blasio,Kerryn T. Westcott,Margaret J. Morris,Larissa Prior,Julie A. Owens,Mary E. Wlodek +7 more
TL;DR: Early life is identified as a target for intervention to prevent later diabetes after prenatal restraint in males, and being born small and exposed to an impaired lactational environment adversely affects adult glucose tolerance and first-phase insulin secretion, but improving lactation partially ameliorates this condition.
Glucose Tolerance by Uteroplacental Insufficiency in Male Rat Offspring Improved Lactational Nutrition and Postnatal Growth Ameliorates Impairment of
Jeffrey S. Robinson,Christopher W. Pugh,Alun M. Davies,Peter Carmeliet,K. van Geyte,D. Teixeira,Antonio Diez-Juan,José López-Barneo,Keith M. Channon,Henrik Oster,B. Wijeyekoon,A. I. Sutherland,A. Grosfeld,Julián Aragonés,Denis Gallagher,Alberto Pascual,Craig A. Lygate,L. G. Nicholls,Maarten P. Koeners,Branko Braam,D. M. van der Giezen,Roel Goldschmeding,Jaap A. Joles,Mary E. Wlodek,Andrew L. Siebel,A. L. Mibus,M. J. De Blasio,Kerryn T. Westcott,Margaret J. Morris,Julie A. Owens +29 more