A
Abigail Pajulas
Publications - 12
Citations - 65
Abigail Pajulas is an academic researcher. The author has contributed to research in topics: Medicine & Immunology. The author has an hindex of 4, co-authored 12 publications receiving 65 citations.
Papers
More filters
Journal ArticleDOI
An IL-9–pulmonary macrophage axis defines the allergic lung inflammatory environment
Yongyao Fu,Jocelyn Wang,Baohua Zhou,Abigail Pajulas,Hongyu Gao,Baskar Ramdas,Byunghee Koh,Benjamin J. Ulrich,Shuangshuang Yang,Reuben Kapur,Jean-Christophe Renauld,Sophie Paczesny,Yunlong Liu,Robert M. Tighe,Paula Licona-Limón,Richard A. Flavell,Shogo Takatsuka,Daisuke Kitamura,Robert I. Tepper,Jie Sun,Mark H. Kaplan +20 more
TL;DR: It is found that IL-9 mediates proallergic activities in the lungs by targeting lung macrophages, identified as key cellular targets of IL- 9 during allergic disease that subsequently amplify type 2 inflammatory responses.
Journal ArticleDOI
Allergic airway recall responses require IL-9 from resident memory CD4+ T cells
Benjamin J. Ulrich,Rakshin Kharwadkar,Michelle Chu,Abigail Pajulas,Charanya Muralidharan,Byunghee Koh,Yongyao Fu,Hongyu Gao,Tristan Hayes,Hong-Ming Zhou,Nick P. Goplen,Andrew S. Nelson,Yunlong Liu,Amelia K. Linnemann,Matthew J. Turner,Paula Licona-Limón,Richard A. Flavell,Jie Sun,Mark H. Kaplan +18 more
TL;DR: IL-9 primarily came from multifunctional CD4+ T cell resident memory (Trm) populations present in the lungs of mice, and targeting IL-9+ Trm in the lung during seasonal allergies might abrogate lung inflammation.
Journal ArticleDOI
Mouse pulmonary interstitial macrophages mediate the pro-tumorigenic effects of IL-9
Yongyao Fu,Abigail Pajulas,Jocelyn Wang,Baohua Zhou,Anthony Cannon,Cherry Cheuk Lam Cheung,Jun Zhang,Huaxin Zhou,Amanda Fisher,David T. Omstead,Sabrina Khan,Lei Han,Jean-Christophe Renauld,Sophie Paczesny,Hongyu Gao,Yunlong Liu,Lei Yang,Robert M. Tighe,Paula Licona-Limón,Richard A. Flavell,Shogo Takatsuka,Daisuke Kitamura,Jie Sun,Basar Bilgicer,Catherine R. Sears,Kai Yang,Mark H. Kaplan +26 more
TL;DR: In this article , the authors show that IL-9 signaling is associated with poor outcomes in patients with various forms of lung cancer, and is required for lung tumor growth in multiple mouse models.
Journal ArticleDOI
Mouse pulmonary interstitial macrophages mediate the pro-tumorigenic effects of IL-9
Yongyao Fu,Abigail Pajulas,Jocelyn Wang,Baohua Zhou,Anthony Cannon,Cherry Cheuk Lam Cheung,Jun Zhang,Huaxin Zhou,Amanda Fisher,David T. Omstead,Sabrina Khan,Lei Han,Jean-Christophe Renauld,Sophie Paczesny,Hongyu Gao,Yunlong Liu,Lei Yang,Robert M. Tighe,Paula Licona-Limón,Richard A. Flavell,Shogo Takatsuka,Daisuke Kitamura,Jie Sun,Basar Bilgicer,Catherine R. Sears,Kai Yang,Mark H. Kaplan +26 more
TL;DR: In this paper , the authors show that IL-9 signaling is associated with poor outcomes in patients with various forms of lung cancer, and is required for lung tumor growth in multiple mouse models.
Journal ArticleDOI
γδ T cell-mediated Wound Healing is Diminished by Allergic Skin Inflammation.
Jocelyn Wang,Abigail Pajulas,Yongyao Fu,Djamilatou Adom,Wenwu Zhang,Andrew S. Nelson,Dan F. Spandau,Mark H. Kaplan +7 more
TL;DR: This article showed that atopic skin inflammation results in a dramatic decrease in the presence of the Vγ3+ dendritic epidermal T-cell population of γδ T cells in the skin.