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Achim Rody
Researcher at University of Lübeck
Publications - 242
Citations - 6083
Achim Rody is an academic researcher from University of Lübeck. The author has contributed to research in topics: Breast cancer & Cancer. The author has an hindex of 38, co-authored 204 publications receiving 5191 citations. Previous affiliations of Achim Rody include Ludwig Maximilian University of Munich & Saarland University.
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Journal ArticleDOI
A New Molecular Predictor of Distant Recurrence in ER-Positive, HER2-Negative Breast Cancer Adds Independent Information to Conventional Clinical Risk Factors
Martin Filipits,Margaretha Rudas,Raimund Jakesz,Peter Dubsky,Florian Fitzal,Christian F. Singer,Otto Dietze,Richard Greil,Andrea Jelen,Paul Sevelda,Christa Freibauer,Volkmar Müller,Fritz Jänicke,Marcus Schmidt,Heinz Kölbl,Achim Rody,Manfred Kaufmann,Werner Schroth,Hiltrud Brauch,Matthias Schwab,Peter Fritz,Karsten Weber,Inke Sabine Feder,Guido Hennig,Ralf Kronenwett,Mathias Gehrmann,Michael Gnant +26 more
TL;DR: A gene expression signature predicting the likelihood of distant recurrence in patients with estrogen receptor–positive, HER2-negative breast cancer treated with adjuvant endocrine therapy is developed and validated.
Journal ArticleDOI
T-cell metagene predicts a favorable prognosis in estrogen receptor-negative and HER2-positive breast cancers
Achim Rody,Uwe Holtrich,Laos Pusztai,Cornelia Liedtke,Regine Gaetje,E. Ruckhaeberle,Christine Solbach,Lars Hanker,A. Ahr,Dirk Metzler,Knut Engels,Thomas Karn,Manfred Kaufmann +12 more
TL;DR: Precise definitions of the specific subtypes of immune cells in the tumor can be accomplished from microarray data, and all known prognostic gene signatures uniformly assign poor prognosis to all ER-negative tumors.
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Microarray analysis of altered sphingolipid metabolism reveals prognostic significance of sphingosine kinase 1 in breast cancer
Eugen Ruckhäberle,Achim Rody,Knut Engels,Regine Gaetje,Gunter von Minckwitz,Susanne Schiffmann,Sabine Grösch,Gerd Geisslinger,Uwe Holtrich,Thomas Karn,Manfred Kaufmann +10 more
TL;DR: The correlation of SPHK1 with a poor prognosis as well as its high expression among ER negative tumors are in line with the antiapoptotic and proliferative properties of its product sphingosine-1-phosphate.
Journal ArticleDOI
A clinically relevant gene signature in triple negative and basal-like breast cancer
Achim Rody,Thomas Karn,Cornelia Liedtke,Lajos Pusztai,E. Ruckhaeberle,Lars Hanker,Regine Gaetje,Christine Solbach,A. Ahr,Dirk Metzler,Marcus Schmidt,Volkmar Müller,Uwe Holtrich,Manfred Kaufmann +13 more
TL;DR: A ratio of high B-cell presence and low IL-8 activity as a powerful new prognostic marker for TNBC is described and inhibition of theIL-8 pathway also represents an attractive novel therapeutic target for this disease.
Journal ArticleDOI
Management of venous port systems in oncology: a review of current evidence
S. Vescia,A. K. Baumgärtner,Volker R. Jacobs,Marion Kiechle-Bahat,Achim Rody,S. Loibl,Nadia Harbeck +6 more
TL;DR: This article reviews the current literature on long-term complications of venous port systems, focusing on infection and thrombosis, and concludes that routine anticoagulation cannot be recommended.