A
Adrian Liston
Researcher at Babraham Institute
Publications - 243
Citations - 15051
Adrian Liston is an academic researcher from Babraham Institute. The author has contributed to research in topics: Immune system & Medicine. The author has an hindex of 52, co-authored 207 publications receiving 12103 citations. Previous affiliations of Adrian Liston include University of Massachusetts Medical School & University of Adelaide.
Papers
More filters
Journal ArticleDOI
Foxp3+ follicular regulatory T cells control the germinal center response
Michelle A. Linterman,Wim Pierson,Sau K. Lee,Axel Kallies,Shimpei Kawamoto,Tim F. Rayner,Monika Srivastava,Devina Divekar,Laura L. Beaton,Jennifer J. Hogan,Sidonia Fagarasan,Adrian Liston,Kenneth G. C. Smith,Carola G. Vinuesa +13 more
TL;DR: A population of Foxp3+Blimp-1+CD4+ T cells constituting 10–25% of the CXCR5highPD-1highCD4- T cells found in the germinal center after immunization with protein antigens are described.
Journal ArticleDOI
Phenotype molding of stromal cells in the lung tumor microenvironment.
Diether Lambrechts,Els Wauters,Bram Boeckx,Sara Aibar,David Nittner,Oliver T. Burton,Ayse Bassez,Herbert Decaluwé,Andreas Pircher,Kathleen Van den Eynde,Birgit Weynand,Erik Verbeken,Paul De Leyn,Adrian Liston,Johan Vansteenkiste,Peter Carmeliet,Stein Aerts,Bernard Thienpont +17 more
TL;DR: A comprehensive single-cell analysis of the lung cancer microenvironment reveals marked heterogeneity of transcriptional networks that defines novel clinically relevant stromal cell populations.
Journal ArticleDOI
How informative is the mouse for human gut microbiota research
Thi Loan Anh Nguyen,Thi Loan Anh Nguyen,Sara Vieira-Silva,Sara Vieira-Silva,Adrian Liston,Jeroen Raes,Jeroen Raes +6 more
TL;DR: The intrinsic similarities and differences that exist between the two systems are discussed, and the human and murine core gut microbiota are compared based on a meta-analysis of currently available datasets.
Journal ArticleDOI
Aire regulates negative selection of organ-specific T cells
TL;DR: It is shown that Aire deficiency causes almost complete failure to delete the organ-specific cells in the thymus, indicating that autoimmune polyendocrinopathy syndrome 1 is caused by failure of a specialized mechanism for deleting forbidden T cell clones.
Journal Article
Foxp3(+) follicular regulatory T cells control the germinal centre response
Michelle A. Linterman,Wim Pierson,Sau K. Lee,Axel Kallies,Shimpei Kawamoto,Sidonia Fagarasan,Adrian Liston,Carola G. Vinuesa,Kenneth G. C. Smith +8 more
TL;DR: In the absence of T FR cells, an outgrowth of non–antigen-specific B cells in germinal centers leads to fewer antigen-specific cells, and the T FH differentiation pathway is co-opted by T reg cells to control the Germinal center response.