A
Andrea Scaloni
Researcher at National Research Council
Publications - 379
Citations - 14635
Andrea Scaloni is an academic researcher from National Research Council. The author has contributed to research in topics: Proteome & Peptide sequence. The author has an hindex of 61, co-authored 379 publications receiving 13096 citations. Previous affiliations of Andrea Scaloni include University of Siena & University of Naples Federico II.
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Journal ArticleDOI
Crystal structure of the catalytic domain of the tumor-associated human carbonic anhydrase IX
Vincenzo Alterio,Mika Hilvo,Anna Di Fiore,Claudiu T. Supuran,Peiwen Pan,Seppo Parkkila,Andrea Scaloni,Jaromir Pastorek,Silvia Pastorekova,Carlo Pedone,Andrea Scozzafava,Simona Maria Monti,Giuseppina De Simone +12 more
TL;DR: On the basis of the structural differences observed between CA IX and the other membrane-associated α-CAs, further prospects for the rational drug design of isozyme-specific CA inhibitors are proposed, given that inhibition of this enzyme shows antitumor activity both in vitro and in vivo.
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Proteins as biomarkers of oxidative/nitrosative stress in diseases: The contribution of redox proteomics
Isabella Dalle-Donne,Andrea Scaloni,Daniela Giustarini,Eleonora Cavarra,Gianluca Tell,Giuseppe Lungarella,Roberto Colombo,Ranieri Rossi,Aldo Milzani +8 more
TL;DR: The study of oxidative/nitrosative modifications, investigated by redox proteomics, is contributing to establish a relationship between pathological hallmarks of disease and protein structural and functional abnormalities, enabling early detection of diseases.
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A Novel White Laccase from Pleurotus ostreatus
TL;DR: Two laccase isoenzymes produced by Pleurotus ostreatus were purified and fully characterized, revealing clear homology with laccases from other microorganisms and showing remarkable high stability with respect to both pH and temperature.
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Biochemical characterization of CA IX, one of the most active carbonic anhydrase isozymes.
Mika Hilvo,Lina Baranauskiene,Anna Maria Salzano,Andrea Scaloni,Daumantas Matulis,Alessio Innocenti,Andrea Scozzafava,Simona Maria Monti,Anna Di Fiore,Giuseppina De Simone,Mikaela Lindfors,Janne Jänis,Jarkko Valjakka,Silvia Pastorekova,Jaromir Pastorek,Markku S. Kulomaa,Henri R. Nordlund,Claudiu T. Supuran,Seppo Parkkila +18 more
TL;DR: Investigations on the oligomerization and stability of the enzymes revealed that both recombinant proteins form dimers that are stabilized by intermolecular disulfide bond(s).
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Purification, structural characterization, cloning and immunocytochemical localization of chemoreception proteins from Schistocerca gregaria
Sergio Angeli,Francesca Ceron,Andrea Scaloni,Maria Chiara Monti,Gaia Monteforti,Antonio Minnocci,Ruggero Petacchi,Paolo Pelosi +7 more
TL;DR: The experimental data suggest that the proteins described here could be involved in contact chemoreception in Orthoptera, in disagreement with the hypothesis that this class of proteins is involved in the CO2-sensing cascade.