C
Carlo Selmi
Researcher at Humanitas University
Publications - 437
Citations - 18189
Carlo Selmi is an academic researcher from Humanitas University. The author has contributed to research in topics: Primary biliary cirrhosis & Medicine. The author has an hindex of 68, co-authored 394 publications receiving 15194 citations. Previous affiliations of Carlo Selmi include University of California, Davis & University of Milan.
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Journal ArticleDOI
Risk Factors and Comorbidities in Primary Biliary Cirrhosis: A Controlled Interview-Based Study of 1032 Patients
M. Eric Gershwin,Carlo Selmi,Carlo Selmi,Howard J. Worman,Ellen B. Gold,Mitchell Watnik,Jessica Utts,Keith D. Lindor,Marshall M. Kaplan,John M. Vierling +9 more
TL;DR: Environmental factors, possibly including infectious agents through urinary tract infections or chemicals contained in cigarette smoke, may induce PBC in genetically susceptible individuals and exogenous estrogens may also contribute to explain the female predominance of the disease.
Journal ArticleDOI
Probiotics and immunity
Andrea T. Borchers,Carlo Selmi,Carlo Selmi,Frederick J. Meyers,Carl L. Keen,M. Eric Gershwin +5 more
TL;DR: Promising results have been obtained with probiotics in the treatment of human inflammatory diseases of the intestine and in the prevention and treatment of atopic eczema in neonates and infants, however, the findings are too variable to allow firm conclusions as to the effectiveness of specific Probiotics in these conditions.
Journal ArticleDOI
Primary biliary cirrhosis in monozygotic and dizygotic twins: Genetics, epigenetics, and environment ☆
Carlo Selmi,Carlo Selmi,Marlyn J. Mayo,Nancy Bach,Hiromi Ishibashi,Pietro Invernizzi,Robert G. Gish,Stuart C. Gordon,Harlan I. Wright,Bruce Zweiban,Mauro Podda,M. Eric Gershwin +11 more
TL;DR: The concordance rate of PBC in identical twins is among the highest reported in autoimmunity, and discordant pairs were identified, indicating that either epigenetic factors and/or environment play a critical role.
Journal ArticleDOI
Genome-wide meta-analyses identify three loci associated with primary biliary cirrhosis
Xiangdong Liu,Pietro Invernizzi,Yue Lu,Roman Kosoy,Yan Lu,Ilaria Bianchi,Mauro Podda,Chun Xu,Gang Xie,Fabio Macciardi,Fabio Macciardi,Carlo Selmi,Carlo Selmi,Sara Lupoli,Russell Shigeta,Michael Ransom,Ana Lleo,Ana Lleo,Annette Lee,Andrew Mason,Robert P. Myers,Kevork M. Peltekian,Cameron N. Ghent,Francesca Bernuzzi,Massimo Zuin,Floriano Rosina,Elisabetta Borghesio,Annarosa Floreani,Roberta Lazzari,Grazia Anna Niro,Angelo Andriulli,Luigi Muratori,Paolo Muratori,Piero Luigi Almasio,Pietro Andreone,Marzia Margotti,Maurizia Rossana Brunetto,Barbara Coco,Domenico Alvaro,Maria Consiglia Bragazzi,Fabio Marra,Alessandro Pisano,Cristina Rigamonti,Massimo Colombo,Marco Marzioni,Antonio Benedetti,Luca Fabris,Mario Strazzabosco,Mario Strazzabosco,Piero Portincasa,Vincenzo Palmieri,Claudio Tiribelli,Lory Saveria Crocè,S. Bruno,Sonia Rossi,Maria Vinci,Cleofe Prisco,Alberto Mattalia,Pierluigi Toniutto,Antonio Picciotto,Andrea Galli,Carlo Ferrari,Silvia Colombo,Giovanni Casella,Lorenzo Morini,Nicola Caporaso,Agostino Colli,Giancarlo Spinzi,Renzo Montanari,Peter K. Gregersen,E. Jenny Heathcote,Gideon M. Hirschfield,Katherine A. Siminovitch,Christopher I. Amos,M. Eric Gershwin,Michael F. Seldin +75 more
TL;DR: A genome-wide association screen for primary biliary cirrhosis risk alleles was performed in an Italian cohort, and a combined meta-analysis using a Canadian dataset identified newly associated loci at SPIB.
Journal ArticleDOI
Interleukin-17 and innate immunity in infections and chronic inflammation
TL;DR: The data discussed in this review cumulatively indicate that innate-derived IL-17 constitutes a major element in the altered immune response against self antigens or the perpetuation of inflammation, particularly at mucosal sites.