Aimo Kannt

TL;DR: Sarcopenia should be considered in all older patients who present with observed declines in physical function, strength, or overall health, and patients who meet these criteria should further undergo body composition assessment using dual energy x-ray absorptiometry with sarcopenia being defined using currently validated definitions.

TL;DR: There was no up-regulation of ACE2 mRNA/protein expression and activity in lung, heart and aorta tissue in ibuprofen-treated mice in comparison to untreated mice, and viral load was significantly reduced by both flurbiprofen and ib uprofen at high concentrations.

TL;DR: Baseline serum CN1 levels were associated with presence and progression of renal function decline in a cohort of T2D patients, and confirmation in larger cohorts with longer follow-up observation periods will be required to fully establish CN1 as a biomarker of DKD.

TL;DR: GuiltyTargets-Covid-19 as discussed by the authors is a machine learning supported web tool to identify novel candidate drug targets using six bulk and three single cell RNA-Seq datasets, together with a lung tissue specific protein-protein interaction network.

TL;DR: The presence and extent of bladder enlargement vary markedly across diabetes models, particularly type 2 diabetes models; the data do not support the idea that bladder enlargements is primarily driven by glucose levels/glucosuria.