A
Akira Arisawa
Researcher at Mercian Corporation
Publications - 46
Citations - 1059
Akira Arisawa is an academic researcher from Mercian Corporation. The author has contributed to research in topics: Hydroxylation & Gene. The author has an hindex of 20, co-authored 46 publications receiving 982 citations.
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Journal ArticleDOI
Hydroxylation of testosterone by bacterial cytochromes P450 using the Escherichia coli expression system.
Hitosi Agematu,Naoki Matsumoto,Yoshikazu Fujii,Hiroki Kabumoto,Satoru Doi,Kazuhiro Machida,Jun Ishikawa,Akira Arisawa +7 more
TL;DR: Two hundred thirteen cytochrome P450 (P450) genes were collected from bacteria and expressed based on an Escherichia coli expression system to test their hydroxylation ability to testosterone.
Journal ArticleDOI
Regioselective biooxidation of (+)-valencene by recombinant E. coli expressing CYP109B1 from Bacillus subtilis in a two-liquid-phase system
TL;DR: The biphasic reaction system described in this work presents an attractive way for the production of (+)-nootkatone (4), as it is safe and can easily be controlled and scaled up.
Journal ArticleDOI
Genome Sequence of Kitasatospora setae NBRC 14216T: An Evolutionary Snapshot of the Family Streptomycetaceae
Natsuko Ichikawa,Akio Oguchi,Haruo Ikeda,Jun Ishikawa,Shigeru Kitani,Yumi Watanabe,Sanae Nakamura,Yoko Katano,Emi Kishi,Machi Sasagawa,Akiho Ankai,Shigehiro Fukui,Yoshimi Hashimoto,Sachi Kamata,Misa Otoguro,Satoshi Tanikawa,Takuya Nihira,Sueharu Horinouchi,Yasuo Ohnishi,Masayuki Hayakawa,Tomohisa Kuzuyama,Akira Arisawa,Fumiki Nomoto,Hiromi Miura,Yoko Takahashi,Nobuyuki Fujita +25 more
TL;DR: The complete genome sequence of K. setae NBRC 14216T is determined as the first Streptomycetaceae genome other than Streptococci genus, and multilocus phylogenetic analysis based on amino acid sequences unequivocally placed K.setae outside the Streptomeces genus.
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Metabolism of mono- and dichloro-dibenzo-p-dioxins by Phanerochaete chrysosporium cytochromes P450.
Noriyuki Kasai,Shinichi Ikushiro,Raku Shinkyo,Kaori Yasuda,Shinji Hirosue,Akira Arisawa,Hirofumi Ichinose,Hiroyuki Wariishi,Toshiyuki Sakaki +8 more
TL;DR: The white-rot fungus Phanerochaete chrysosporium possesses biodegradative capabilities of polychlorinated dibenzo-p-dioxins, and a microsomal P cCYP designated as PcCYP11a3 has the highest activity toward PCDDs among the known CYPs derived from microorganisms.
Journal ArticleDOI
Insight into functional diversity of cytochrome P450 in the white-rot basidiomycete Phanerochaete chrysosporium: involvement of versatile monooxygenase.
Shinji Hirosue,Masahiro Tazaki,Nobuhiro Hiratsuka,Satoshi Yanai,Hiroki Kabumoto,Raku Shinkyo,Akira Arisawa,Toshiyuki Sakaki,Hiroshi Tsunekawa,Osamu Johdo,Hirofumi Ichinose,Hiroyuki Wariishi +11 more
TL;DR: It is suggested that multifunctional properties of the versatile PcCYPs would play crucial roles in diversification of fungal metabolic systems involved in xenobiotic detoxification and provide new insights that could also expedite practical applications in the biotechnology sector.