A
Alberto Malesci
Researcher at University of Milan
Publications - 213
Citations - 10585
Alberto Malesci is an academic researcher from University of Milan. The author has contributed to research in topics: Inflammatory bowel disease & Cancer. The author has an hindex of 47, co-authored 199 publications receiving 8910 citations. Previous affiliations of Alberto Malesci include University of Genoa & Utrecht University.
Papers
More filters
Journal ArticleDOI
Tumour-associated macrophages as treatment targets in oncology
Alberto Mantovani,Federica Marchesi,Federica Marchesi,Alberto Malesci,Alberto Malesci,Luigi Laghi,Paola Allavena +6 more
TL;DR: It is surmised that TAMs can provide tools to tailor the use of cytoreductive therapies and immunotherapy in a personalized medicine approach, and that TAM-focused therapeutic strategies have the potential to complement and synergize with both chemotherapy and immunotherapies.
Journal ArticleDOI
Inflammation and coagulation in inflammatory bowel disease: The clot thickens.
TL;DR: Overall, an overview is provided that the coagulation system represents an important, though previously underestimated, component of IBD pathogenesis, and may be a possible target for therapeutic intervention.
Journal ArticleDOI
VEGF-A Links Angiogenesis and Inflammation in Inflammatory Bowel Disease Pathogenesis
Franco Scaldaferri,Stefania Vetrano,Miquel Sans,Vincenzo Arena,Giuseppe Straface,Egidio Stigliano,Alessandro Repici,Andreas Sturm,Alberto Malesci,Julián Panés,Seppo Ylä-Herttuala,Claudio Fiocchi,Silvio Danese +12 more
TL;DR: VEGF-A appears to be a novel mediator of IBD by promoting intestinal angiogenesis and inflammation, and agents that block VEGf-A signaling might reduce intestinal inflammation in patients with IBD.
Journal ArticleDOI
Occurrence of Tertiary Lymphoid Tissue Is Associated with T-Cell Infiltration and Predicts Better Prognosis in Early-Stage Colorectal Cancers
Giuseppe Di Caro,Francesca Bergomas,Fabio Grizzi,Andrea Doni,Paolo Bianchi,Alberto Malesci,Luigi Laghi,Paola Allavena,Alberto Mantovani,Federica Marchesi +9 more
TL;DR: Evidence is provided that TLT is associated with lymphocyte infiltration in colorectal cancer, providing a pathway of recruitment for TILs, representing a novel prognostic biomarker for coloreCTal cancer.
Journal ArticleDOI
Unique role of junctional adhesion molecule-a in maintaining mucosal homeostasis in inflammatory bowel disease.
Stefania Vetrano,Maria Rescigno,Maria Rosaria Cera,C. Correale,Cristiano Rumio,Andrea Doni,Massimo Fantini,Andreas Sturm,Elena Monica Borroni,Alessandro Repici,Massimo Locati,Alberto Malesci,Elisabetta Dejana,Elisabetta Dejana,Silvio Danese +14 more
TL;DR: The results show a nonredundant and novel role of JAM-A in controlling mucosal homeostasis by regulating the integrity and permeability of epithelial barrier function.