Stuart Montgomery

TL;DR: The construction of a depression rating scale designed to be particularly sensitive to treatment effects is described, and its capacity to differentiate between responders and non-responders to antidepressant treatment was better than the HRS, indicating greater sensitivity to change.

TL;DR: An interdisciplinary group of 15 psychiatrists, psychologists and clinical pharmacologists was formed under the auspices of the Swedish Medical Research Council to study the problem of evaluating change in psychiatric disorders with treatment and decided to construct a new scale covering psychopathological variables likely to be changed by treatment.

TL;DR: This article reviews the available data on social functioning in depression and provides clinical guidelines and opinion on this important and expanding field and it is becoming clear that not all treatments are equally effective in relieving the impaired social functioning associated with depressive disorders.

TL;DR: The findings provide a set of 11 relevant clinical variables associated with treatment resistance in major depressive disorder that can be explored at the clinical level and show that comorbid anxiety disorder is the most powerful clinical factor associated with TRD.

TL;DR: The proposed criteria are intended for therapeutic trials in TRD, combining the evaluation of treatment efficiency and the validation of the concept of TRD itself, including major depression with poor response to two adequate trials of different classes of antidepressants.