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Alexander I. Gray
Researcher at Strathclyde Institute of Pharmacy and Biomedical Sciences
Publications - 296
Citations - 7233
Alexander I. Gray is an academic researcher from Strathclyde Institute of Pharmacy and Biomedical Sciences. The author has contributed to research in topics: Eriostemon & Premna. The author has an hindex of 41, co-authored 292 publications receiving 6648 citations. Previous affiliations of Alexander I. Gray include University of Strathclyde & Netaji Subhas Institute of Technology.
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Journal ArticleDOI
Coumarins in the Rutaceae
TL;DR: The biogenesis, structural diversity and distribution of simple, furano- and pyranocoumarins in the Rutaceae is reviewed and the potential value of these compounds as taxonomic markers and their possible functions are discussed.
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Polymeric Chitosan‐based Vesicles for Drug Delivery
Ijeoma F. Uchegbu,Andreas G. Schätzlein,Laurence Tetley,Alexander I. Gray,Julieann Sludden,Soryia Siddique,Erasto Mosha +6 more
TL;DR: A simple carbohydrate polymer glycol chitosan (degree of polymerization 800 approx.) has been investigated for its ability to form polymeric vesicle drug carriers and the attachment of hydrophobic groups should yield an amphiphilic polymer capable of self‐assembly into vesicles.
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The release of model macromolecules may be controlled by the hydrophobicity of palmitoyl glycol chitosan hydrogels
Lee Martin,Clive G. Wilson,Fariba Koosha,Laurence Tetley,Alexander I. Gray,Sevda Şenel,Ijeoma F. Uchegbu +6 more
TL;DR: A non-covalently cross-linked palmitoyl glycol chitosan (GCP) hydrogel has been evaluated as an erodible controlled release system for the delivery of hydrophilic macromolecules and was bioadhesive but less so than hydroxypropylmethylcellulose, Carbopol 974NF (7:3) tablets.
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Bacterial resistance modifying agents from Lycopus europaeus
TL;DR: Two-fold potentiation of the activities of these antibiotics was observed against two strains of S. aureus that were highly resistant to these agents due to the presence of the multidrug efflux mechanisms Tet(K) (tetracycline resistance) and Msr(A) (macrolide resistance).
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The effects of cardamonin on lipopolysaccharide-induced inflammatory protein production and MAP kinase and NFkappaB signalling pathways in monocytes/macrophages.
TL;DR: The effect of the natural product cardamonin, upon lipopolysaccharide (LPS)‐induced inflammatory gene expression is examined in order to attempt to pinpoint the mechanism of action.