Alexander Leemans

TL;DR: The brain-wide, localized ventral diencephalon and hypothalamic connectivity differences clearly show a heretofore underestimated direct and/or indirect effect of hypocretin deficiency on microstructural white matter composition, presumably resulting from a combination of lower axonal density, lower myelination and/ or greater axon diameter.

TL;DR: This work quantitatively investigates the cognitive processes and associated neuroanatomy of spatial working memory in people with 22q11 Deletion syndrome compared to matched controls and examines whether there are significant between‐group differences in spatialWorking memory using task related fMRI, Voxel based morphometry and white matter fiber tractography.

TL;DR: White matter is susceptible to radiation with some regional variability where diffusivity metrics demonstrate the largest relative sensitivity, suggesting that dMRI is a promising tool in assessing microstructural changes after RT, which can help in understanding treatment-induced cognitive decline.

TL;DR: The feasibility of an advanced 3 T MRI protocol that allowed differences to be determined between patients and healthy controls was shown, confirming the potential of this technique to assess pathological mechanisms in SMA.

TL;DR: In this paper, a comparison of five different methods that estimate mappings between scanners for diffusion MRI data harmonisation is presented, and the results show that cross-vendor harmonization and spatial/angular resolution enhancement of single-shell diffusion data sets can be performed reliably, although some challenges remain.