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Alexander Leemans
Researcher at Utrecht University
Publications - 306
Citations - 21500
Alexander Leemans is an academic researcher from Utrecht University. The author has contributed to research in topics: Diffusion MRI & Fractional anisotropy. The author has an hindex of 64, co-authored 289 publications receiving 17932 citations. Previous affiliations of Alexander Leemans include Australian Catholic University & Cardiff University.
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Journal ArticleDOI
Effect of Fixed-Density Thresholding on Structural Brain Networks: A Demonstration in Cerebral Small Vessel Disease.
Bruno M. de Brito Robalo,Naomi Vlegels,Jil Meier,Alexander Leemans,Geert Jan Biessels,Yael D. Reijmer +5 more
TL;DR: It is concluded that moderate fixed-density thresholds can successfully be applied to control for the effects of density in structural brain network analysis.
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Cross-site harmonization of multi-shell diffusion MRI measures based on rotational invariant spherical harmonics (RISH)
A. De Luca,Süheyla Çetin Karayumak,Alexander Leemans,Yogesh Rathi,Stephan P. Swinnen,Jolien Gooijers,Amanda Clauwaert,Roald Bahr,Stian Bahr Sandmo,Nir Sochen,David Kaufmann,Marc Muehlmann,Geert Jan Biessels,Inga K. Koerte,Ofer Pasternak +14 more
TL;DR: In this paper , rotation invariant spherical harmonics (RISH) features were used to harmonize multiscale diffusion tensor imaging (DTI) and NODDI metrics.
Journal ArticleDOI
Post-mortem diffusion MRI of the cervical spine and its nerve roots
Wieke Haakma,Wieke Haakma,Martijn Froeling,Michael Pedersen,Lars Uhrenholt,Perla Douven,Alexander Leemans,Lene Warner Thorup Boel +7 more
TL;DR: Examination of the architectural configuration and the microstructural substrate of the cervical spine and its nerve roots with post-mortem (PM) diffusion tensor imaging (DTI) in non-fixed subjects suggests that PMDTI will be helpful in the assessment of head and neck injuries in a forensic setting.
Journal ArticleDOI
1269 – Reduced fractional anisotropy in the uncinate fasciculus in patients with major depression carrying the met-allele of the Val66Met brain-derived neurotrophic factor genotype
Angela Carballedo,Francesco Amico,I. Ugwu,Andrew J. Fagan,Ciara Fahey,Derrek Morris,James F. Meaney,Alexander Leemans,Thomas Frodl +8 more
TL;DR: The met-allele of the BDNF polymorphism seems to render subjects more vulnerable for dysfunctions associated with the UF, a tract known to be related to negative emotional-cognitive processing bias, declarative memory problems, and autonoetic self awareness.
Towards quantification of the brain's sheet structure : evaluation of the discrete Lie bracket
Chantal M. W. Tax,T.C.J. Dela Haije,Andrea Fuster,Remco Duits,Max A. Viergever,Luc Florack,Alexander Leemans +6 more
TL;DR: Tax et al. as mentioned in this paper discussed the convergence of the BRAIN'S sheet structure and the divergence of the lie-branching structure of the brain, and proposed an approach to evaluate the difference between the two layers.