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Alexander Leemans
Researcher at Utrecht University
Publications - 306
Citations - 21500
Alexander Leemans is an academic researcher from Utrecht University. The author has contributed to research in topics: Diffusion MRI & Fractional anisotropy. The author has an hindex of 64, co-authored 289 publications receiving 17932 citations. Previous affiliations of Alexander Leemans include Australian Catholic University & Cardiff University.
Papers
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Proceedings ArticleDOI
Assessment of methods to extract the mid-sagittal plane from brain MR images
TL;DR: In this paper, the authors classify the methods into three distinct classes: feature-based, global symmetry based, and local symmetry based methods, based on the shape or intensity of interhemispheric fissure to extract the mid-sagittal plane.
Journal ArticleDOI
Psychotic experiences in childhood are associated with increased structural integrity of the left arcuate fasciculus - A population-based case-control study.
Niamh Dooley,Niamh Dooley,Erik O'Hanlon,Erik O'Hanlon,Colm Healy,Amy Adair,Amy Adair,Conor McCandless,David Coppinger,Ian Kelleher,Mary Clarke,Alexander Leemans,Thomas Frodl,Mary Cannon,Mary Cannon +14 more
TL;DR: This study is the first to investigate links between arcuate fasciculus diffusivity and psychotic experiences in a population sample of children, and focuses on individual differences in one such tract, the arcuate Fasciculus.
Journal ArticleDOI
The effect of gradient nonlinearities on fiber orientation estimates from spherical deconvolution of diffusion magnetic resonance imaging data.
Fenghua Guo,Alberto De Luca,Greg D. Parker,Derek K. Jones,Max A. Viergever,Alexander Leemans,Chantal M. W. Tax,Chantal M. W. Tax +7 more
TL;DR: Simulations show that using the effective b‐matrix can improve dRL fiber orientation estimation and reduces angular deviations, while CSD can be more robust to gradient nonlinearity depending on the implementation, and an extension of dRL to take into account gradient imperfections, without the need of data interpolation.
Journal ArticleDOI
Early prediction of unilateral cerebral palsy in infants at risk : MRI versus the hand assessment for infants
Nienke Wagenaar,Cornelia H. Verhage,Linda S. de Vries,Bram P L van Gasselt,Corine Koopman,Alexander Leemans,Floris Groenendaal,Manon J.N.L. Benders,Niek E. van der Aa +8 more
TL;DR: Predicting USCP after UPBI is reliable using asymmetry of the CST on MRI, as well as clinical hand assessment, while DTI tractography provides strongest predictive information, while HAI specifically aids to prognosis of USCP at later age points.
Journal ArticleDOI
Progressive microstructural changes of the occipital cortex in Huntington's disease.
Omar F. F. Odish,Robert H. A. M. Reijntjes,Simon J.A. van den Bogaard,Raymund A.C. Roos,Alexander Leemans +4 more
TL;DR: Findings suggest that measures obtained from the occipital cortex can serve as sensitive longitudinal biomarkers for disease progression in preHD-B and early HD and could be used to assess potential effects of proposed disease modifying therapies.