A
Alexandra Giatromanolaki
Researcher at Democritus University of Thrace
Publications - 360
Citations - 26647
Alexandra Giatromanolaki is an academic researcher from Democritus University of Thrace. The author has contributed to research in topics: Angiogenesis & Cancer. The author has an hindex of 66, co-authored 340 publications receiving 22956 citations. Previous affiliations of Alexandra Giatromanolaki include John Radcliffe Hospital.
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Journal ArticleDOI
Potential role of bcl-2 as a suppressor of tumour angiogenesis in non-small-cell lung cancer.
Michael I. Koukourakis,Alexandra Giatromanolaki,Kenneth J. O'Byrne,R. M. Whitehouse,Denis C. Talbot,Kevin C. Gatter,Adrian L. Harris +6 more
TL;DR: In this article, the authors examined the relationship between tumour vascularization, a measure of tumour angiogenesis, and bcl-2 and p53 expression in operable non-small-cell lung cancer (NSCLC).
Potential role of bcl-2 as a suppressor of tumour angiogenesis in non- small-cell lung cancer
Michael I. Koukourakis,Alexandra Giatromanolaki,Kenneth J. O'Byrne,R. M. Whitehouse,Denis C. Talbot,Kevin C. Gatter,Adrian L. Harris +6 more
TL;DR: The results suggest that the anti‐apoptotic gene bcl‐2 plays a role in regulating tumour angiogenesis and the improved prognosis reported in b cl‐2‐positive NSCLC may be related to low tumour vascularization.
Journal ArticleDOI
'Invading edge vs. inner' (edvin) patterns of vascularization: an interplay between angiogenic and vascular survival factors defines the clinical behaviour of non-small cell lung cancer.
Alexandra Giatromanolaki,Michael I. Koukourakis,E. Sivridis,Kenneth J. O'Byrne,Kevin C. Gatter,Adrian L. Harris +5 more
TL;DR: It is suggested that tumour factors regulating angiogenesis and vascular survival are not identical and may contribute to the evaluation of the effectiveness of different therapeutic approaches, namely vascular targeting vs. anti‐angiogenesis.
Invading edge vs. inner (edvin) patterns of vascularization : an interplay between angiogenic and vascular survival factors defines the clinical behaviour of non-small cell lung cancer
Alexandra Giatromanolaki,Michael I. Koukourakis,E. Sivridis,Kenneth J. O'Byrne,Kevin C. Gatter,Adrian L. Harris +5 more
TL;DR: In this article, microvessel score (MS) as well as the single endothelial cell score (ECS) in the invading edge and in inner areas of non-small cell lung carcinomas (NSCLCs) were compared.
Journal Article
Coexpression of MUC1 glycoprotein with multiple angiogenic factors in non-small cell lung cancer suggests coactivation of angiogenic and migration pathways.
Alexandra Giatromanolaki,Michael I. Koukourakis,Efthimios Sivridis,Keneth O'Byrne,Giles Cox,Philip E. Thorpe,Kevin C. Gatter,Adrian L. Harris +7 more
TL;DR: The present study suggests the existence of an early genetic event leading to the activation of both migration and angiogenesis pathways in non-small cell lung cancer.