A
Alexandra Giatromanolaki
Researcher at Democritus University of Thrace
Publications - 360
Citations - 26647
Alexandra Giatromanolaki is an academic researcher from Democritus University of Thrace. The author has contributed to research in topics: Angiogenesis & Cancer. The author has an hindex of 66, co-authored 340 publications receiving 22956 citations. Previous affiliations of Alexandra Giatromanolaki include John Radcliffe Hospital.
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Journal ArticleDOI
Ectonucleotidase CD73 and CD39 expression in non-small cell lung cancer relates to hypoxia and immunosuppressive pathways.
Alexandra Giatromanolaki,Maria Kouroupi,Stamatia Pouliliou,Achilleas Mitrakas,Fatma Hasan,Aglaia Pappa,Michael I. Koukourakis +6 more
TL;DR: Ectonucleotidases are up-regulated in cancer cells, CAFs, and TILs in lung tumors, linked with regulatory TIL-phenotype and PD-L1 up-regulation by cancer cells.
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Immunohistochemical expression of metalloproteinases MMP-2 and MMP-9 in abdominal aortic aneurysms: correlation with symptoms and aortic diameter.
Efstathios Papalambros,Fragiska Sigala,S. Georgopoulos,Charalambos Menekakos,Alexandra Giatromanolaki,Elias Bastounis,Efthymios Sivridis +6 more
TL;DR: The MMP-9 activity in AAA is a determinant of the aneurysm size, but it is not related to clinical manifestations, and there was no relation between AAA size and M MP-2 activity.
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Prognostic role of angiogenesis in operable carcinoma of the gallbladder.
Alexandra Giatromanolaki,Efthimios Sivridis,Michael I. Koukourakis,Alexandros Polychronidis,Constantinos Simopoulos +4 more
TL;DR: The assessment of intratumoral angiogenesis in patients with operable gallbladder carcinomas may be useful in predicting prognosis and, perhaps, in decision making for postoperative adjuvant treatment.
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Intensified autophagy compromises the efficacy of radiotherapy against prostate cancer
Michael I. Koukourakis,Dimitra Kalamida,Achilleas Mitrakas,Stamatia Pouliliou,Sofia Kalamida,Efthimios Sivridis,Alexandra Giatromanolaki +6 more
TL;DR: High base line autophagy activity and cell ability to sustain functional autophagosome and lysosomal consumption define resistance of prostate cancer cells to radiotherapy.
Journal ArticleDOI
Repression of the autophagic response sensitises lung cancer cells to radiation and chemotherapy.
Ilias V. Karagounis,Dimitra Kalamida,Achilleas Mitrakas,Stamatia Pouliliou,Maria Liousia,Alexandra Giatromanolaki,Michael I. Koukourakis +6 more
TL;DR: The ability of lung cancer cells to survive after irradiation at 4 Gy depends on their ability to sustain a functional autophagic flux, which results in increased radiosensitivity and susceptibility to various chemotherapy agents.