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Alexandre Boyer
Researcher at Université de Montréal
Publications - 117
Citations - 3536
Alexandre Boyer is an academic researcher from Université de Montréal. The author has contributed to research in topics: Medicine & Intensive care. The author has an hindex of 28, co-authored 98 publications receiving 2787 citations. Previous affiliations of Alexandre Boyer include Baylor College of Medicine.
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Journal ArticleDOI
Initiation Strategies for Renal-Replacement Therapy in the Intensive Care Unit
Stéphane Gaudry,David Hajage,Frédérique Schortgen,Laurent Martin-Lefevre,Bertrand Pons,Eric Boulet,Alexandre Boyer,Guillaume Chevrel,Nicolas Lerolle,Dorothée Carpentier,Nicolas de Prost,Alexandre Lautrette,Anne Bretagnol,Julien Mayaux,Saad Nseir,Bruno Mégarbane,Marina Thirion,Jean-Marie Forel,Julien Maizel,Hodane Yonis,Philippe Markowicz,Guillaume Thiery,Florence Tubach,Jean-Damien Ricard,Didier Dreyfuss +24 more
TL;DR: In a trial involving critically ill patients with severe acute kidney injury, a delayed strategy averted the need for renal-replacement therapy in an appreciable number of patients and found no significant difference with regard to mortality.
Journal ArticleDOI
WNT4 is required for normal ovarian follicle development and female fertility
Alexandre Boyer,Evelyne Lapointe,Xiaofeng Zheng,Robert G. Cowan,Huaiguang Li,Susan M. Quirk,Francesco J. DeMayo,JoAnne S. Richards,Derek Boerboom,Derek Boerboom +9 more
TL;DR: RT-PCR analyses showed that WNT4 regulates the expression of Star, Cyp11a1, and Cyp19, steroidogenic genes previously identified as downstream targets of the WNT signaling effector CTNNB1, which indicates that Wnt4 is required for normal antral follicle development and may act by regulating granulosa cell functions including steroidogenesis.
Journal ArticleDOI
WNT signaling in ovarian follicle biology and tumorigenesis.
TL;DR: The current knowledge of WNT signaling in ovarian follicles is reviewed, highlighting both the great promise and the many unresolved questions of this emerging field of research.
Journal ArticleDOI
Physiologic Effects of High-Flow Nasal Cannula Oxygen in Critical Care Subjects
TL;DR: Compared with conventional oxygen therapy, HFNC improved inspiratory effort and oxygenation in subjects with acute hypoxemic respiratory failure, and is an alternative to conventional oxygen Therapy.
Journal ArticleDOI
Influence of surgical treatment timing on mortality from necrotizing soft tissue infections requiring intensive care management
Alexandre Boyer,Frédéric Vargas,Fanny Coste,Elodie Saubusse,Yves Castaing,G Gbikpi-Benissan,Gilles Hilbert,Didier Gruson +7 more
TL;DR: In patients with NSTI and septic shock, hospital mortality is influenced by the timing of surgical treatment.