F
Frédérique Schortgen
Researcher at French Institute of Health and Medical Research
Publications - 99
Citations - 7714
Frédérique Schortgen is an academic researcher from French Institute of Health and Medical Research. The author has contributed to research in topics: Intensive care & Intensive care unit. The author has an hindex of 32, co-authored 93 publications receiving 6679 citations. Previous affiliations of Frédérique Schortgen include University of Paris & Claude Bernard University Lyon 1.
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Journal ArticleDOI
Use of procalcitonin to reduce patients' exposure to antibiotics in intensive care units (PRORATA trial): a multicentre randomised controlled trial.
Lila Bouadma,Charles-Edouard Luyt,Florence Tubach,Christophe Cracco,Antonio Alvarez,Carole Schwebel,Frédérique Schortgen,Sigismond Lasocki,Benoit Veber,Monique Dehoux,Maguy Bernard,Blandine Pasquet,Bernard Regnier,Christian Brun-Buisson,Jean Chastre,Michel Wolff +15 more
TL;DR: A procalcitonin-guided strategy to treat suspected bacterial infections in non-surgical patients in intensive care units could reduce antibiotic exposure and selective pressure with no apparent adverse outcomes.
Journal ArticleDOI
Initiation Strategies for Renal-Replacement Therapy in the Intensive Care Unit
Stéphane Gaudry,David Hajage,Frédérique Schortgen,Laurent Martin-Lefevre,Bertrand Pons,Eric Boulet,Alexandre Boyer,Guillaume Chevrel,Nicolas Lerolle,Dorothée Carpentier,Nicolas de Prost,Alexandre Lautrette,Anne Bretagnol,Julien Mayaux,Saad Nseir,Bruno Mégarbane,Marina Thirion,Jean-Marie Forel,Julien Maizel,Hodane Yonis,Philippe Markowicz,Guillaume Thiery,Florence Tubach,Jean-Damien Ricard,Didier Dreyfuss +24 more
TL;DR: In a trial involving critically ill patients with severe acute kidney injury, a delayed strategy averted the need for renal-replacement therapy in an appreciable number of patients and found no significant difference with regard to mortality.
Journal ArticleDOI
Effects of hydroxyethylstarch and gelatin on renal function in severe sepsis: a multicentre randomised study
Frédérique Schortgen,Jean-Claude Lacherade,F. Bruneel,Isabelle Cattaneo,François Hemery,François Lemaire,Laurent Brochard +6 more
TL;DR: The use of this preparation of hydroxyethylstarch as a plasma-volume expander is an independent risk factor for ARF in patients with severe sepsis or septic shock.
Journal ArticleDOI
Treatment of acute hypoxemic nonhypercapnic respiratory insufficiency with continuous positive airway pressure delivered by a face mask: A randomized controlled trial.
Christophe Delclaux,Erwan L'Her,Corinne Alberti,Jordi Mancebo,Fekri Abroug,Giorgio Conti,Claude Guérin,Frédérique Schortgen,Yannick Lefort,Massimo Antonelli,Eric Lepage,François Lemaire,Laurent Brochard +12 more
TL;DR: Despite early physiologic improvement, CPAP neither reduced the need for intubation nor improved outcomes in patients with acute hypoxemic, nonhypercapnic respiratory insufficiency primarily due to acute lung injury.
Journal ArticleDOI
Association of Noninvasive Ventilation With Nosocomial Infections and Survival in Critically Ill Patients
Emmanuelle Girou,Frédérique Schortgen,Christophe Delclaux,Christian Brun-Buisson,François Blot,Yannick Lefort,François Lemaire,Laurent Brochard +7 more
TL;DR: Use of NIV instead of mechanical ventilation is associated with a lower risk of nosocomial infections, less antibiotic use, shorter length of ICU stay, and lower mortality.