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Alexandre Thiéry
Researcher at University of Bern
Publications - 6
Citations - 173
Alexandre Thiéry is an academic researcher from University of Bern. The author has contributed to research in topics: Population bottleneck & Background selection. The author has an hindex of 4, co-authored 6 publications receiving 104 citations. Previous affiliations of Alexandre Thiéry include Swiss Institute of Bioinformatics.
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Journal ArticleDOI
Background selection and biased gene conversion affect more than 95% of the human genome and bias demographic inferences.
Fanny Pouyet,Fanny Pouyet,Simon Aeschbacher,Simon Aeschbacher,Simon Aeschbacher,Alexandre Thiéry,Alexandre Thiéry,Laurent Excoffier,Laurent Excoffier +8 more
TL;DR: High-quality human genomic data is used to show that purifying selection at linked sites and GC-biased gene conversion together affect as much as 95% of the variants of the genome, and identifies a set of SNPs that are mostly unaffected by BGS or gBGC.
Journal ArticleDOI
Recent Evolutionary History of Tigers Highlights Contrasting Roles of Genetic Drift and Selection.
Ellie E. Armstrong,Anubhab Khan,Ryan W. Taylor,Alexandre Gouy,Alexandre Gouy,Gili Greenbaum,Gili Greenbaum,Alexandre Thiéry,Alexandre Thiéry,Jonathan T. L. Kang,Jonathan T. L. Kang,Sergio A. Redondo,Stefan Prost,Gregory S. Barsh,Christopher B. Kaelin,Sameer Phalke,Anup Chugani,Martin Gilbert,Martin Gilbert,Dale G. Miquelle,Arun Zachariah,Udayan Borthakur,Anuradha Reddy,Edward Louis,Oliver A. Ryder,Yadvendradev V. Jhala,Dmitri A. Petrov,Laurent Excoffier,Laurent Excoffier,Elizabeth A. Hadly,Uma Ramakrishnan +30 more
TL;DR: In this paper, the authors re-sequenced 65 individual tiger genomes representing most extant subspecies with a specific focus on tigers from India and found strong genetic differentiation between the putative tiger subspecies.
Posted ContentDOI
Recent evolutionary history of tigers highlights contrasting roles of genetic drift and selection
Ellie E. Armstrong,Anubhab Khan,Ryan W. Taylor,Alexandre Gouy,Alexandre Gouy,Gili Greenbaum,Alexandre Thiéry,Alexandre Thiéry,Jonathan T. L. Kang,Jonathan T. L. Kang,Sergio A. Redondo,Stefan Prost,Gregory S. Barsh,Christopher B. Kaelin,Sameer Phalke,Anup Chugani,Martin Gilbert,Martin Gilbert,Dale G. Miquelle,Arun Zachariah,Udayan Borthakur,Anuradha Reddy,Edward Louis,Oliver A. Ryder,Yadvendradev V. Jhala,Dmitri A. Petrov,Laurent Excoffier,Laurent Excoffier,Elizabeth A. Hadly,Uma Ramakrishnan +29 more
TL;DR: The results support the isolation of Amur and Sumatran tigers, while geneflow between Malayan and South Asian tigers may be considered, while the impacts of ongoing connectivity loss on the health and persistence of tigers in India should be closely monitored.
Posted ContentDOI
The mixed genetic origin of the first farmers of Europe
Nina Marchi,Laura Winkelbach,Ilektra Schulz,Maxime Brami,Zuzana Hofmanová,Jens Blöcher,Carlos S. Reyna-Blanco,Yoan Diekmann,Alexandre Thiéry,Adamandia Kapopoulou,Piuz,Susanne Kreutzer,Figarska Sm,Elissavet Ganiatsou,Pukaj A,Necmi Karul,Fokke Gerritsen,Pechtl J,Joris Peters,Andrea Zeeb-Lanz,Eva Lenneis,Maria Teschler-Nicola,Sevasti Triantaphyllou,Sofija Stefanović,Christina Papageorgopoulou,Daniel Wegmann,Joachim Burger,Laurent Excoffier +27 more
TL;DR: The analyses provide a time frame and resolve the genetic origins of early European farmers, and highlight the impact of Late Pleistocene climatic fluctuations that caused the fragmentation, merging and reexpansion of human populations in SW Asia and Europe, and eventually led to the world's first agricultural populations.
Peer ReviewDOI
Author response: Background selection and biased gene conversion affect more than 95% of the human genome and bias demographic inferences
Fanny Pouyet,Fanny Pouyet,Simon Aeschbacher,Simon Aeschbacher,Simon Aeschbacher,Alexandre Thiéry,Alexandre Thiéry,Laurent Excoffier,Laurent Excoffier +8 more