F
Fanny Pouyet
Researcher at Swiss Institute of Bioinformatics
Publications - 13
Citations - 422
Fanny Pouyet is an academic researcher from Swiss Institute of Bioinformatics. The author has contributed to research in topics: Background selection & Gene. The author has an hindex of 6, co-authored 13 publications receiving 324 citations. Previous affiliations of Fanny Pouyet include University of Lyon & École normale supérieure de Lyon.
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Journal ArticleDOI
Bio++: Efficient Extensible Libraries and Tools for Computational Molecular Evolution
Laurent Guéguen,Sylvain Gaillard,Sylvain Gaillard,Sylvain Gaillard,Bastien Boussau,Bastien Boussau,Manolo Gouy,Mathieu Groussin,Nicolas C. Rochette,Thomas Bigot,David Fournier,Fanny Pouyet,Vincent Cahais,Aurélien Bernard,Celine Scornavacca,Benoit Nabholz,Annabelle Haudry,Loïc Dachary,Nicolas Galtier,Khalid Belkhir,Julien Y. Dutheil,Julien Y. Dutheil +21 more
TL;DR: The second major release of the Bio++ libraries is presented, which provides an extended set of classes and methods that notably provide built-in access to sequence databases and new data structures for handling and manipulating sequences from the omics era, such as multiple genome alignments and sequencing reads libraries.
Journal ArticleDOI
Background selection and biased gene conversion affect more than 95% of the human genome and bias demographic inferences.
Fanny Pouyet,Fanny Pouyet,Simon Aeschbacher,Simon Aeschbacher,Simon Aeschbacher,Alexandre Thiéry,Alexandre Thiéry,Laurent Excoffier,Laurent Excoffier +8 more
TL;DR: High-quality human genomic data is used to show that purifying selection at linked sites and GC-biased gene conversion together affect as much as 95% of the variants of the genome, and identifies a set of SNPs that are mostly unaffected by BGS or gBGC.
Journal ArticleDOI
Recombination, meiotic expression and human codon usage
TL;DR: It is demonstrated here that SCU is not driven by constraints on tRNA abundance, but by large-scale variation in GC-content, caused by meiotic recombination, via the non-adaptive process of GC-biased gene conversion (gBGC).
Journal ArticleDOI
Transition from Background Selection to Associative Overdominance Promotes Diversity in Regions of Low Recombination.
Kimberly J. Gilbert,Kimberly J. Gilbert,Fanny Pouyet,Fanny Pouyet,Laurent Excoffier,Laurent Excoffier,Stephan Peischl,Stephan Peischl +7 more
TL;DR: A model describing how and under which conditions multi-locus dynamics can amplify the effects of associative overdominance (AOD) is presented and demonstrates that AOD may play an important role in the evolution of low-recombination regions of many species.
Posted ContentDOI
Transition from background selection to associative overdominance promotes diversity in regions of low recombination
Kimberly J. Gilbert,Kimberly J. Gilbert,Fanny Pouyet,Fanny Pouyet,Laurent Excoffier,Laurent Excoffier,Stephan Peischl,Stephan Peischl +7 more
TL;DR: Simulations show that multi-locus AOD can increase diversity in low recombination regions much more strongly than previously appreciated and demonstrate that AOD may play an important role in the evolution of low recombinations regions of many species.