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Alexis Perez-Gonzalez
Researcher at University of Melbourne
Publications - 13
Citations - 792
Alexis Perez-Gonzalez is an academic researcher from University of Melbourne. The author has contributed to research in topics: Biology & Anemone. The author has an hindex of 6, co-authored 7 publications receiving 633 citations. Previous affiliations of Alexis Perez-Gonzalez include European Bioinformatics Institute.
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Journal ArticleDOI
Tissue-specific analysis of chromatin state identifies temporal signatures of enhancer activity during embryonic development.
Stefan Bonn,Robert P. Zinzen,Charles Girardot,E. Hilary Gustafson,Alexis Perez-Gonzalez,Nicolas Delhomme,Yad Ghavi-Helm,Bartek Wilczyński,Andrew Riddell,Eileen E. M. Furlong +9 more
TL;DR: This new approach to obtain cell type–specific information on chromatin state and RNA polymerase II (Pol II) occupancy within the multicellular Drosophila melanogaster embryo identifies dynamic enhancer usage, an essential step in deciphering developmental networks.
Journal ArticleDOI
Outer Membrane Vesicles Prime and Activate Macrophage Inflammasomes and Cytokine Secretion In Vitro and In Vivo.
Jessica D. Cecil,Neil M O'Brien-Simpson,Jason C Lenzo,James A Holden,William Singleton,Alexis Perez-Gonzalez,Ashley Mansell,Eric C. Reynolds +7 more
TL;DR: In this article, the authors investigated the immune-modulatory effects of P. gingivalis, T. denticola, and T. forsythia OMVs on monocytes and differentiated macrophages.
Journal ArticleDOI
Cell type-specific chromatin immunoprecipitation from multicellular complex samples using BiTS-ChIP
Stefan Bonn,Robert P. Zinzen,Alexis Perez-Gonzalez,Andrew Riddell,Anne-Claude Gavin,Eileen E. M. Furlong +5 more
TL;DR: The key advantages of this method are the covalent cross-linking before embryo dissociation, which preserves the transcriptional context, and the use of FACS of nuclei, yielding very high purity.
Journal ArticleDOI
Comparative assessment of fluorescent transgene methods for quantitative imaging in human cells
Robert Mahen,Birgit Koch,Malte Wachsmuth,Antonio Z. Politi,Alexis Perez-Gonzalez,Julia Mergenthaler,Yin Cai,Jan Ellenberg +7 more
TL;DR: This study shows that the choice of fluorescence-tagging method fundamentally influences the ability to image the activity of the mitotic kinase Aurora B.
Journal ArticleDOI
Intracellular bacteria are common and taxonomically diverse in cultured and in hospite algal endosymbionts of coral reefs.
Justin Maire,Sam K. Girvan,Sophie E. Barkla,Alexis Perez-Gonzalez,David J. Suggett,Linda L. Blackall,Madeleine J. H. van Oppen,Madeleine J. H. van Oppen +7 more
TL;DR: In this paper, the authors describe the localization and composition of the bacterial communities associated with cultures of 11 Symbiodiniaceae strains from nine species and six genera, and reveal that bacteria are present inside the cells as well as closely associated with their external cell surface.