N
Nicolas Delhomme
Researcher at Swedish University of Agricultural Sciences
Publications - 67
Citations - 3962
Nicolas Delhomme is an academic researcher from Swedish University of Agricultural Sciences. The author has contributed to research in topics: Transcriptome & Medicine. The author has an hindex of 22, co-authored 57 publications receiving 3194 citations. Previous affiliations of Nicolas Delhomme include German Cancer Research Center & European Bioinformatics Institute.
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Journal ArticleDOI
The Norway spruce genome sequence and conifer genome evolution.
Björn Nystedt,Nathaniel R. Street,Anna Wetterbom,Andrea Zuccolo,Yao-Cheng Lin,Douglas G. Scofield,Francesco Vezzi,Nicolas Delhomme,Stefania Giacomello,Andrey Alexeyenko,Riccardo Vicedomini,Kristoffer Sahlin,Ellen Sherwood,Malin Elfstrand,Lydia Gramzow,Kristina Holmberg,Jimmie Hällman,Olivier Keech,Lisa Klasson,Maxim Koriabine,Melis Kucukoglu,Max Käller,Johannes Luthman,Fredrik Lysholm,Totte Niittylä,Åke Olson,Nemanja Rilakovic,Carol Ritland,Josep A. Rosselló,Juliana Stival Sena,Thomas Svensson,Carlos Talavera-López,Günter Theißen,Hannele Tuominen,Kevin Vanneste,Zhiqiang Wu,Bo Zhang,Philipp Zerbe,Lars Arvestad,Lars Arvestad,Rishikesh P. Bhalerao,Joerg Bohlmann,Jean Bousquet,Rosario Garcia Gil,Torgeir R. Hvidsten,Torgeir R. Hvidsten,Pieter J. de Jong,John MacKay,Michele Morgante,Kermit Ritland,Björn Sundberg,Stacey Lee Thompson,Yves Van de Peer,Björn Andersson,Ove Nilsson,Pär K. Ingvarsson,Joakim Lundeberg,Stefan Jansson +57 more
TL;DR: The draft assembly of the 20-gigabase genome of Norway spruce (Picea abies), the first available for any gymnosperm, is presented, revealing numerous long (>10,000 base pairs) introns, gene-like fragments, uncharacterized long non-coding RNAs and short RNAs, which opens up new genomic avenues for conifer forestry and breeding.
Journal ArticleDOI
Tissue-specific analysis of chromatin state identifies temporal signatures of enhancer activity during embryonic development.
Stefan Bonn,Robert P. Zinzen,Charles Girardot,E. Hilary Gustafson,Alexis Perez-Gonzalez,Nicolas Delhomme,Yad Ghavi-Helm,Bartek Wilczyński,Andrew Riddell,Eileen E. M. Furlong +9 more
TL;DR: This new approach to obtain cell type–specific information on chromatin state and RNA polymerase II (Pol II) occupancy within the multicellular Drosophila melanogaster embryo identifies dynamic enhancer usage, an essential step in deciphering developmental networks.
Journal ArticleDOI
The Genomic and Transcriptomic Landscape of a HeLa Cell Line
Jonathan J M Landry,Paul Theodor Pyl,Tobias Rausch,Thomas Zichner,Manu M. Tekkedil,Adrian M. Stütz,Anna Jauch,Raeka S. Aiyar,Gregoire Pau,Nicolas Delhomme,Julien Gagneur,Jan O. Korbel,Wolfgang Huber,Lars M. Steinmetz +13 more
TL;DR: This study performed DNA and RNA sequencing of a HeLa Kyoto cell line and analyzed its mutational portfolio and gene expression profile, providing the first detailed account of genomic variants in the HeLa genome.
Journal ArticleDOI
The Plant Genome Integrative Explorer Resource: PlantGenIE.org
David Sundell,Chanaka Mannapperuma,Sergiu Netotea,Nicolas Delhomme,Yao-Cheng Lin,Andreas Sjödin,Yves Van de Peer,Yves Van de Peer,Stefan Jansson,Torgeir R. Hvidsten,Torgeir R. Hvidsten,Nathaniel R. Street +11 more
TL;DR: The integrated PlantGenIE.org platform for exploration of Populus, conifer and Arabidopsis genomics data, which includes expression networks and associated visualization tools is presented, facilitating both community contributions to annotation improvement and tools supporting use of the included data resources to inform biological insight.
Journal ArticleDOI
AspWood: High-Spatial-Resolution Transcriptome Profiles Reveal Uncharacterized Modularity of Wood Formation in Populus tremula
David Sundell,Nathaniel R. Street,Manoj Kumar,Ewa J. Mellerowicz,Melis Kucukoglu,Christoffer Johnsson,Vikash Kumar,Chanaka Mannapperuma,Nicolas Delhomme,Ove Nilsson,Hannele Tuominen,Edouard Pesquet,Edouard Pesquet,Urs Fischer,Totte Niittylä,Björn Sundberg,Torgeir R. Hvidsten,Torgeir R. Hvidsten +17 more
TL;DR: High spatial resolution of the AspWood large-scale data set enabled identification of novel roles for characterized genes involved in xylan and cellulose biosynthesis, regulators of xylem vessel and fiber differentiation and lignification and regulation of the transcriptome underlying cambial growth and wood formation.