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Alf A. Lindberg
Researcher at Karolinska Institutet
Publications - 439
Citations - 10581
Alf A. Lindberg is an academic researcher from Karolinska Institutet. The author has contributed to research in topics: Shigella flexneri & Crystal structure. The author has an hindex of 49, co-authored 439 publications receiving 10396 citations. Previous affiliations of Alf A. Lindberg include Stockholm University & Praxis.
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Journal ArticleDOI
Identification of the carbohydrate receptor for Shiga toxin produced by Shigella dysenteriae type 1.
Alf A. Lindberg,J E Brown,Nicklas Strömberg,M Westling-Ryd,Joachim E. Schultz,Karl-Anders Karlsson +5 more
TL;DR: Glycolipid-bound, bilayer-close galabiose is proposed as the functional receptor for membrane penetration of the toxin, while galabioses bound in glycoproteins affords binding sites but is not able to mediate penetration.
Journal ArticleDOI
Structural Studies on the Hexose Region of the Core in Lipopolysaccharides from Enterobacteriaceae
TL;DR: The structures for the hexose regions of cores from Enterobacteriaceae lipopolysaccharides have been investigated, using specific degradations and 1H NMR studies as the principal methods.
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Structural studies on the O-specific side-chains of the cell-wall lipopolysaccharide from Salmonella typhimurium 395 ms
TL;DR: The structure of the O-specific side-chains of the cell-wall lipopolysaccharide of Salmonella typhimurium 395 MS has been investigated and a detailed structure ofThe repeating unit of these side- chains is presented.
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Chemical structure of the lipopolysaccharide of Haemophilus influenzae strain I-69 Rd-/b+. Description of a novel deep-rough chemotype.
Ilkka M. Helander,Buko Lindner,Helmut Brade,Klaus Altmann,Alf A. Lindberg,Ernst Th. Rietschel,Ulrich Zähringer +6 more
TL;DR: The chemical structure of the lipopolysaccharide of a deep-rough mutant (strain I-69 Rd-/b+) of Haemophilus influenzae was investigated and was the first described to contain only one sugar unit linked to lipid A.
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Safety, infectivity, immunogenicity, and in vivo stability of two attenuated auxotrophic mutant strains of Salmonella typhi, 541Ty and 543Ty, as live oral vaccines in humans.
Myron M. Levine,D A Herrington,James R. Murphy,J G Morris,Genevieve Losonsky,Ben D. Tall,Alf A. Lindberg,Stefan B. Svenson,Shahida Baqar,M F Edwards +9 more
TL;DR: All individuals, postvaccination, demonstrated a significant plasma-dependent mononuclear cell inhibition of wild S. typhi, and all vaccinees manifested cell-mediated immune responses.