K
Karl-Anders Karlsson
Researcher at University of Gothenburg
Publications - 183
Citations - 10494
Karl-Anders Karlsson is an academic researcher from University of Gothenburg. The author has contributed to research in topics: Glycolipid & Sialic acid. The author has an hindex of 54, co-authored 183 publications receiving 10315 citations.
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Journal ArticleDOI
Helicobacter pylori SabA adhesin in persistent infection and chronic inflammation.
Jafar Mahdavi,Berit Sondén,Martina Hurtig,Farzad O. Olfat,Farzad O. Olfat,Lina Forsberg,Niamh Roche,Jonas Ångström,Thomas Larsson,Susann Teneberg,Karl-Anders Karlsson,Siiri Altraja,Torkel Wadström,Dangeruta Kersulyte,Douglas E. Berg,Andre Dubois,Christoffer Petersson,Karl-Eric Magnusson,Thomas Norberg,Frank Lindh,Bertil Lundskog,Anna Arnqvist,Lennart Hammarström,Thomas Borén +23 more
TL;DR: The ability of many H. pylori strains to adhere to sialylated glycoconjugates expressed during chronic inflammation might contribute to virulence and the extraordinary chronicity ofH.pylori infection.
Journal ArticleDOI
Identification of the carbohydrate receptor for Shiga toxin produced by Shigella dysenteriae type 1.
Alf A. Lindberg,J E Brown,Nicklas Strömberg,M Westling-Ryd,Joachim E. Schultz,Karl-Anders Karlsson +5 more
TL;DR: Glycolipid-bound, bilayer-close galabiose is proposed as the functional receptor for membrane penetration of the toxin, while galabioses bound in glycoproteins affords binding sites but is not able to mediate penetration.
Journal ArticleDOI
Avian influenza A viruses differ from human viruses by recognition of sialyloligosaccharides and gangliosides and by a higher conservation of the HA receptor-binding site.
Mikhail Matrosovich,A.S. Gambaryan,Susann Teneberg,V. E. Piskarev,S. S. Yamnikova,D. K. Lvov,James S. Robertson,Karl-Anders Karlsson +7 more
TL;DR: The results suggest that the RBS is highly conserved among HA subtypes of avian influenza virus, while that of human viruses displays distinctive genotypic and phenotypic variability.
Journal ArticleDOI
Microbial recognition of target-cell glycoconjugates
TL;DR: Information of conceptual interest, including crystal structures of protein-saccharide complexes and convincing models of target membrane penetration, continues to emerge for viruses and bacterial toxins.
Journal ArticleDOI
Specificity of binding of a strain of uropathogenic Escherichia coli to Gal alpha 1----4Gal-containing glycosphingolipids.
K Bock,Michael E. Breimer,A Brignole,Gunnar C. Hansson,Karl-Anders Karlsson,Göran Larson,Hakon Leffler,B.E. Samuelsson,Nicklas Strömberg,C S Edén +9 more
TL;DR: A strain of Escherichia coli originally isolated from urine of a patient with acute pyelonephritis was studied in detail for binding to glycosphingolipids and showed a bend in the saccharide chain at this disaccharide with a largely hydrophobic surface of the convex side.