A
Alicia Rodríguez-Gascón
Researcher at University of the Basque Country
Publications - 59
Citations - 2008
Alicia Rodríguez-Gascón is an academic researcher from University of the Basque Country. The author has contributed to research in topics: Medicine & Gene delivery. The author has an hindex of 19, co-authored 52 publications receiving 1419 citations.
Papers
More filters
Journal ArticleDOI
Nanostructured lipid carriers: Promising drug delivery systems for future clinics.
Ana Beloqui,María Ángeles Solinís,Alicia Rodríguez-Gascón,António J. Almeida,Véronique Préat +4 more
TL;DR: The understanding of the nanostructured lipid carriers (NLC)-based formulations has improved with continuing research recently, and the result has seen an increase in the use of these in the clinical setting.
Journal ArticleDOI
Augmented Renal Clearance in Critically Ill Patients: A Systematic Review
Idoia Bilbao-Meseguer,Alicia Rodríguez-Gascón,Helena Barrasa,Arantxazu Isla,María Ángeles Solinís +4 more
TL;DR: Augmented renal clearance is a prevalent condition in critically ill patients, especially in young people, with urinary CrCl being the best diagnostic method because mathematical estimates tend to underestimate CrCl.
Journal ArticleDOI
Nanomedicines to Deliver mRNA: State of the Art and Future Perspectives
Itziar Gómez-Aguado,Julen Rodríguez-Castejón,Mónica Vicente-Pascual,Alicia Rodríguez-Gascón,María Ángeles Solinís,Ana del Pozo-Rodríguez +5 more
TL;DR: This manuscript includes a revision of the strategies employed to enhance in vitro transcribed mRNA functionality and efficacy, including the optimization of its stability and translational efficiency, as well as the regulation of its immunostimulatory properties.
Journal ArticleDOI
Budesonide-loaded nanostructured lipid carriers reduce inflammation in murine DSS-induced colitis.
Ana Beloqui,Régis Coco,Mireille Alhouayek,María Ángeles Solinís,Alicia Rodríguez-Gascón,Giulio G. Muccioli,Véronique Préat +6 more
TL;DR: NLCs could be a promising alternative to polymeric nanoparticles as a targeted drug delivery system for IBD treatment, according to the histological scores of the colons.
Journal ArticleDOI
Understanding the mechanism of protamine in solid lipid nanoparticle-based lipofection: The importance of the entry pathway
TL;DR: In spite of the high DNA condensation capacity of protamine and its content in NLS, this does not always lead to an improvement in cell transfection since it may impair some of the limiting steps of the transfections processes.