A
Amanda Khuong
Researcher at Stanford University
Publications - 9
Citations - 2497
Amanda Khuong is an academic researcher from Stanford University. The author has contributed to research in topics: Cancer & Muscle atrophy. The author has an hindex of 7, co-authored 9 publications receiving 1734 citations. Previous affiliations of Amanda Khuong include VA Palo Alto Healthcare System & National Institutes of Health.
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Journal ArticleDOI
The prognostic landscape of genes and infiltrating immune cells across human cancers
Andrew J. Gentles,Aaron M. Newman,Chih Long Liu,Scott V. Bratman,Scott V. Bratman,Weiguo Feng,Dongkyoon Kim,Viswam S. Nair,Yue Xu,Amanda Khuong,Chuong D. Hoang,Maximilian Diehn,Robert B. West,Sylvia K. Plevritis,Ash A. Alizadeh +14 more
TL;DR: A pan-cancer resource and meta-analysis of expression signatures from ∼18,000 human tumors with overall survival outcomes across 39 malignancies is presented and it is found that expression of favorably prognostic genes, including KLRB1 (encoding CD161), largely reflect tumor-associated leukocytes.
Journal ArticleDOI
Predictive radiogenomics modeling of EGFR mutation status in lung cancer.
Olivier Gevaert,Sebastian Echegaray,Amanda Khuong,Chuong D. Hoang,Joseph B. Shrager,Kirstin C. Jensen,Gerald J. Berry,H. Henry Guo,Charles T. Lau,Sylvia K. Plevritis,Daniel L. Rubin,Sandy Napel,Ann N. Leung +12 more
TL;DR: The results show the potential of quantitative imaging to predict molecular properties in a non-invasive manner, as CT imaging is more readily available than biopsies.
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mTORC1 Promotes Denervation-Induced Muscle Atrophy Through a Mechanism Involving the Activation of FoxO and E3 Ubiquitin Ligases
Huibin Tang,Huibin Tang,Ken Inoki,Myung Chang Lee,Myung Chang Lee,Erika Wright,Erika Wright,Andy Khuong,Amanda Khuong,Sista Sugiarto,Matthew Garner,Jihye Paik,Ronald A. DePinho,Daniel Goldman,Kun-Liang Guan,Joseph B. Shrager,Joseph B. Shrager +16 more
TL;DR: It is found that at later stages after denervation of fast-twitch muscle, activation of mTORC1 contributed to atrophy and that denervation-induced atrophy was mitigated by inhibition of m TORC1 with rapamycin, which represents a potential therapeutic target in neurogenic muscle atrophy.
Journal ArticleDOI
Presence of Even a Small Ground-Glass Component in Lung Adenocarcinoma Predicts Better Survival
Mark F. Berry,Rebecca W. Gao,Christian A. Kunder,Leah M. Backhus,Amanda Khuong,Michael A. Kadoch,Ann N. Leung,Joseph B. Shrager +7 more
TL;DR: Patients with resected cN0 lung adenocarcinoma who have even a small GGO component have markedly better survival than patients with PS tumors, which may have implications for both treatment and surveillance strategies.
Journal ArticleDOI
Prediction of EGFR and KRAS mutation in non-small cell lung cancer using quantitative 18 F FDG-PET/CT metrics
Ryogo Minamimoto,Mehran Jamali,Olivier Gevaert,Sebastian Echegaray,Amanda Khuong,Chuong D. Hoang,Joseph B. Shrager,Sylvia K. Plevritis,Daniel L. Rubin,Ann N. Leung,Sandy Napel,Andrew Quon +11 more
TL;DR: Overall, smoking status was the most significant factor for the presence of the EGFR and KRAS mutations in lung cancer overall and the tumor heterogeneity metric 1/COV and SUVmax were both predictive for the EG FR mutations in NSCLC in a univariate analysis.