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Amar G. Chittiboyina
Researcher at University of Mississippi
Publications - 194
Citations - 3508
Amar G. Chittiboyina is an academic researcher from University of Mississippi. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 23, co-authored 162 publications receiving 2912 citations. Previous affiliations of Amar G. Chittiboyina include National Chemical Laboratory & United States Department of Agriculture.
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Journal ArticleDOI
Identification of Telmisartan as a Unique Angiotensin II Receptor Antagonist With Selective PPARγ–Modulating Activity
Stephen C. Benson,Harrihar A. Pershadsingh,Christopher I. Ho,Amar G. Chittiboyina,Prashant V. Desai,Michal Pravenec,N. Qi,Jiaming Wang,Mitchell A. Avery,Theodore W. Kurtz +9 more
TL;DR: In this paper, the authors showed that telmisartan, a structurally unique angiotensin II receptor antagonist used for the treatment of hypertension, can function as a partial agonist of peroxisome proliferator-activated receptor-gamma (PPARgamma) and reduce glucose, insulin, and triglyceride levels in rats fed a high-fat, high-carbohydrate diet.
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Physicochemical Characterization of Berberine Chloride: A Perspective in the Development of a Solution Dosage Form for Oral Delivery
Sunil Kumar Battu,Michael A. Repka,Sindhuri Maddineni,Amar G. Chittiboyina,Mitchell A. Avery,Soumyajit Majumdar +5 more
TL;DR: The physicochemical characteristics of berberine chloride and the complexation of drug with 2-hydroxypropyl-β-cyclodextrin (HPβCD) were evaluated and the feasibility of developing an oral solution dosage form of the drug was demonstrated.
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Type 2 Diabetes and Oral Antihyperglycemic Drugs
Cassia S. Mizuno,Amar G. Chittiboyina,Theodore W. Kurtz,Harrihar A. Pershadsingh,Mitchell A. Avery +4 more
TL;DR: The pros and cons of the six classes of oral hypoglycemic drugs available to treat Type IIabetes are presented and some of the latest advances towards the development of new drugs for the treatment of Type II diabetes are discussed.
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Mechanisms enforcing the estrogen receptor β selectivity of botanical estrogens
Yan Jiang,Ping Gong,Zeynep Madak-Erdogan,Teresa A. Martin,Muthu Jeyakumar,Kathryn E. Carlson,Ikhlas A. Khan,Troy J. Smillie,Amar G. Chittiboyina,Sateesh Chandra Kumar Rotte,William G. Helferich,John A. Katzenellenbogen,Benita S. Katzenellenbogen +12 more
TL;DR: Key and novel mechanistic differences in the estrogenic activities of BEs vs. E2 are revealed, with BEs displaying patterns of activity distinctly different from those seen with E2 and provide valuable information to inform future studies.
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Optical Absorption Study of the Biotin−Avidin Interaction on Colloidal Silver and Gold Particles
TL;DR: In this paper, the effect of avidin on the surface of colloidal silver and gold particles was studied using optical absorption spectroscopy, and the degree of flocculation was quantified using a semi-empirical parameter and the dependence of this parameter on the extent of biotinylation of the colloidal particle surface as well as the concentration in solution was studied to determine the optimum working...