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Amit Anand
Researcher at Cleveland Clinic
Publications - 182
Citations - 11052
Amit Anand is an academic researcher from Cleveland Clinic. The author has contributed to research in topics: Bipolar disorder & Mania. The author has an hindex of 43, co-authored 148 publications receiving 9622 citations. Previous affiliations of Amit Anand include United States Department of Veterans Affairs & Cleveland Clinic Lerner College of Medicine.
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Journal ArticleDOI
Antidepressant effects of ketamine in depressed patients
Robert M. Berman,Angela Cappiello,Amit Anand,Amit Anand,Dan A. Oren,Dan A. Oren,George R. Heninger,Dennis S. Charney,Dennis S. Charney,John H. Krystal,John H. Krystal +10 more
TL;DR: A first placebo-controlled, double-blinded trial to assess the treatment effects of a single dose of an N-methyl-D-aspartate (NMDA) receptor antagonist in patients with depression suggests a potential role for NMDA receptor-modulating drugs in the treatment of depression.
Journal ArticleDOI
Activity and Connectivity of Brain Mood Regulating Circuit in Depression: A Functional Magnetic Resonance Study
Amit Anand,Yu Li,Yang Wang,Jingwei Wu,Sujuan Gao,Lubna Bukhari,Vincent P. Mathews,Andrew J. Kalnin,Mark J. Lowe +8 more
TL;DR: The finding of increased activation of limbic regions and decreased LFBF correlations between ACC and limbic areas is consistent with the hypothesis that decreased cortical regulation of limbics activation in response to negative stimuli may be present in depression.
Journal ArticleDOI
Recent developments in biological activities of chalcones: a mini review.
TL;DR: This review article focuses on the recent developments (2010-2014) on various pharmacological and medicinal aspects of chalcones and their analogues.
Journal ArticleDOI
Glutamate and GABA systems as targets for novel antidepressant and mood-stabilizing treatments
J.H. Krystal,Gerard Sanacora,Hilary P. Blumberg,Amit Anand,Dennis S. Charney,Gerard J. Marek,C N Epperson,Andrew Goddard,Graeme F. Mason +8 more
TL;DR: The preponderance of available evidence suggests that glutamatergic and GABAergic modulation may be an important property of available antidepressant and mood-stabilizing agents.
Journal ArticleDOI
Attenuation of the Neuropsychiatric Effects of Ketamine With Lamotrigine: Support for Hyperglutamatergic Effects of N-methyl-D-aspartate Receptor Antagonists
Amit Anand,Dennis S. Charney,Dan A. Oren,Robert M. Berman,X. S. Hu,Angela Cappiello,J.H. Krystal +6 more
TL;DR: The hypothesis that lamotrigine, a drug reported to inhibit glutamate release, will reduce the neuropsychiatric effects of ketamine in humans is tested and it is suggested that glutamate release-inhibiting drugs may reduce the hyperglutamatergic consequences of NMDA receptor dysfunction implicated in the pathophysiologic processes of neuro psychological illnesses such as schizophrenia.