Amy S. Turmelle

TL;DR: Despite its divergence from known influenza A virus, the bat virus is compatible for genetic exchange with human influenza viruses in human cells, suggesting the potential capability for reassortment and contributions to new pandemic or panzootic influenza A viruses.

TL;DR: Using a data set of hundreds of rabies viruses sampled from 23 North American bat species, a general framework is presented to quantify per capita rates of cross-species transmission and reconstruct historical patterns of viral establishment in new host species using molecular sequence data, which demonstrate diminishing frequencies of both cross- species transmission and host shifts with increasing phylogenetic distance between bat species.

TL;DR: It is suggested that long-term repeated infection of bats may confer significant immunological memory and reduced susceptibility to RABV infection.

TL;DR: Evidence is found that sampling effort, IUCN status, and population genetic structure correlate with observed viral species richness in bats, and that these associations are independent of phylogeny.

TL;DR: Enhanced surveillance, improved diagnostics, increased pathogen detection, and an integrated One Health approach, targeting human, domestic animal and wildlife interfaces, provide modern insights to the ecology of bat lyssaviruses to augment future prevention and control.