Showing papers by "Anders H. Riis published in 2014"
TL;DR: Metformin use was associated with decreased risk of PCa diagnosis, whereas diabetics using other oral hypoglycemics had no decreased risk and other oral antidiabetic medications did not.
122 citations
TL;DR: Among Danish pregnancy planners, cumulative exposure to active cigarette smoking was associated with delayed conception among current and former smokers and time since smoking cessation and passive smoking were not appreciably associated with fecundability.
40 citations
TL;DR: It is identified that acute medical patients often present with non-specific symptoms or complications related to their chronic diseases, particularly cardiovascular diseases and infectious diseases.
40 citations
TL;DR: It is suggested that obesity is a stronger risk factor for early pregnancy losses, and that small stature and low WHR are associated with an increased risk of SAB.
Abstract: The prevalence of obesity is increasing worldwide.1 In Denmark, the prevalence of obesity has exhibited a marked increase within the past 25 to 30 years, particularly for reproductive-aged women, of whom 9.7% were obese in 2006–2007.2 Studies have reported that both obesity3–6 and underweight7,8 are associated with an increased risk of spontaneous abortion (SAB).
Obesity is associated with disturbances in sex hormone metabolism, reproductive disorders,9 intrauterine and urinary tract infections,10 and disruptions in the follicular environment including increased inflammation.11 Although few studies have examined the risk of SAB among underweight women, lower maternal serum leptin levels and poor nutritional status have been hypothesized to increase SAB risk in this group.7,8
Using data from a Danish prospective cohort of pregnancy planners, we examined risk of SAB in relation to selected anthropometric factors, including body mass index (BMI), location of typical weight gain, height, waist circumference (WC), and waist-to-hip ratio (WHR).
39 citations
TL;DR: Previous studies indicate that pre‐admission glucocorticoids increase the risk of perioperative complications, and these findings are consistent with those of previous studies.
Abstract: Summary
Background
Previous studies indicate that pre-admission glucocorticoids increase the risk of perioperative complications.
Aim
To examine whether pre-admission use of glucocorticoids affects 30-day mortality after colorectal cancer (CRC) surgery.
Methods
We conducted a nationwide population-based cohort study by linking Danish medical registries. All residents in Denmark who underwent CRC surgery from 2001 to 2011 were included. We characterised subjects who filled their most recent glucocorticoid prescription ≤90, 91–365 and >365 days before their surgery date as prevalent, recent and former users, respectively. Prevalent users were subgrouped into new (first-ever prescription ≤90 days before surgery date) and continuing users. We estimated 30-day cumulative mortality by the Kaplan–Meier method and corresponding mortality rate ratios (MRRs) using Cox proportional hazard regression, adjusting for potential confounders.
Results
Of the 34 641 CRC patients included, 3966 (11.5%) had filled one or more prescriptions of glucocorticoids within the year before the surgery date. Thirty-day mortality among prevalent users of oral glucocorticoids was 15.0% vs. 7.3% among non-users [MRR = 1.28; 95% confidence interval (CI): 1.03, 1.58]. Among new users, the 30-day mortality was 17.8% (MRR = 1.92; 95% CI: 1.30, 2.83) while it was 14.2% among continuing users (MRR = 1.13; 95% CI: 0.88, 1.44). No associations were found for recent or former use of oral glucocorticoids nor for use of inhaled, intestinal-acting, and mixed glucocorticoids.
Conclusions
Prevalent use, particulary new use, of oral glucocorticoids was associated with markedly increased 30-day mortality after colorectal cancer surgery compared to patients not exposed to any glucocorticoids.
6 citations
TL;DR: The results indicate that birth weight appears not to be an important determinant of fecundability.
Abstract: Objective
To examine the association between a woman's birth weight and her subsequent fecundability.
3 citations
1 citations