Showing papers in "The Journal of Urology in 2014"

TL;DR: The guideline statements offered in this document provide a simple, evidence-based approach to identify high-risk or interested stone-forming patients for whom medical and dietary therapy based on metabolic testing and close follow-up is likely to be effective in reducing stone recurrence.

TL;DR: Genitourinary organ salvage has become increasingly possible as a result of advances in imaging, minimally invasive techniques, and reconstructive surgery and clinicians must strive to approach clinical problems in a creative, multidisciplinary, evidence-based manner to ensure optimal outcomes.

TL;DR: A systematic review and meta-analysis of the published literature was conducted using controlled vocabulary supplemented with key words relating to the relevant concepts of cryptorchidism as discussed by the authors, which yielded 704 articles published from 1980 through 2013 that were used to form a majority of the guideline statements.

TL;DR: The authors' enhanced recovery after surgery protocol expedites bowel function recovery and shortens hospital stay after RC and urinary diversion without an increase in the hospital readmission rates.

TL;DR: The accuracy of multiparametric magnetic resonance imaging for detecting significant prostate cancer before diagnostic biopsy in men with abnormal prostate specific antigen/digital rectal examination was determined and reported by expert radiologists achieved an excellent negative predictive value and a moderate positive predictive value forsignificant prostate cancer.

TL;DR: The dissemination of robotic surgery for partial nephrectomy in the United States has been rapid and safe and the robotic procedure had lower odds than laparoscopic partial ne phrectomy for most study outcomes except hospital charges.

TL;DR: The DOCUMENT study validated that the epigenetic assay was a significant, independent predictor of prostate cancer detection in a repeat biopsy collected an average of 13 months after an initial negative result.

TL;DR: The cell cycle progression score derived from a biopsy sample was associated with adverse outcomes after surgery and indicates that the score can be used at disease diagnosis to better define patient prognosis and enable more appropriate clinical care.

TL;DR: The results of this trial support the external validity of this platform and may be the next step in the evolution of prostate cancer management.

TL;DR: Better diagnostic performance was noted for anti-3-[(18)F]FACBC positron emission tomography-computerized tomography than for ProstaScint® ((111)In-capromab pendetide) single photon emission computerized tomographic-computerizing tomography for prostate carcinoma recurrence.

TL;DR: Exosomes derived from the urine of patients with bladder cancer contains bioactive molecules such as EDIL-3, and it is found that shEDil-3 exosomes did not facilitate angiogenesis, and urothelial and endothelial cell migration.

TL;DR: In this paper, a new early recovery after surgery concept was compared to a more conservative regimen in patients undergoing radical cystectomy for bladder cancer, and a total of 101 consecutive patients were prospectively randomized to early recover after surgery (62) or a conservative regimen (39).

TL;DR: While some increase resulted from localized disease, the highest annual percent change was in grade III tumors, indicating more aggressive disease, continued monitoring of trends and epidemiological study are warranted to determine risk factors.

TL;DR: An autologous cell seeded biodegradable scaffold for bladder augmentation as an alternative to traditional enterocystoplasty in children/adolescents with medically refractory neurogenic bladder did not improve bladder compliance or capacity and serious adverse events surpassed an acceptable safety standard.

TL;DR: The presence of high risk features identifies patients with a poor prognosis who are most likely to benefit from neoadjuvant chemotherapy, while many of those with low risk disease can undergo surgery up front with good expectations and avoid chemotherapy associated toxicity.

TL;DR: Junior and senior clinicians showed a dramatic adoption of endoscopic techniques and logistic regression models assessed how surgeon specific attributes affected the way that upper tract stones were treated.

TL;DR: Use of magnetic resonance imaging for targeting prostate biopsies has the potential to reduce the sampling error associated with conventional biopsy by providing better disease localization and sampling.

TL;DR: It is believed that restaging resection should be performed before initiating bacillus Calmette-Guérin therapy in all patients with high risk nonmuscle invasive bladder cancer because failure to repeat resection significantly increases the risk of recurrence.

TL;DR: Sarcopenia in women was a predictor of major complications after radical cystectomy after bladder cancer treatment, and further research confirming sarcopenia as a useful predictor of complications would support the development of targeted interventions to mitigate the untoward effects of sarc Openia before cancer surgery.

TL;DR: Flexible dose fesoterodine significantly improved urgency urinary incontinence episodes and other outcomes vs placebo, and was generally well tolerated.

TL;DR: (partial) penectomy and lymphadenectomy were associated with more problems with orgasm, body image, life interference and urination, and additional longitudinal studies are warranted to evaluate individual changes with time in these outcomes.

TL;DR: Black men with very low risk prostate cancer at diagnosis have a significantly higher prevalence of anterior cancer foci that are of higher grade and larger volume, and enhanced imaging or anterior zone sampling may detect these significant anterior tumors, improving the outcome in black men considering active surveillance.

TL;DR: The data suggest that surgically induced Chronic kidney disease has a lower rate of functional decline and less impact on survival than chronic kidney disease due to medical causes.

TL;DR: Improvement in adherence and persistence with antimuscarinic medication should be an important goal in the development of new drugs for overactive bladder and urinary incontinence.

TL;DR: In men with prostate cancer on active surveillance the number of previous prostate biopsies is associated with a significant risk of infectious complications and every previous biopsy increases therisk of infectious complication.

TL;DR: Multidisciplinary management of anticoagulant/antiplatelet medications for patients with recent thromboembolic events, mechanical cardiac valves, atrial fibrillation and cardiac stents would reduce the high morbidity and mortality of inexpertly discontinuing or modifying these lifesaving therapies.

TL;DR: The incidence of kidney stone disease in children is increasing, yet few randomized clinical trials or high quality observational studies have assessed whether dietary or pharmacological interventions decrease the recurrence of kidney stones in children.

TL;DR: Criteria for active surveillance for men with high suspicion targets on imaging should be reevaluated when multiparametric magnetic resonance imaging-ultrasound fusion guided prostate biopsy is used.

TL;DR: In this pilot study magnetic resonance imaging-ultrasound fusion biopsy allowed for the prediction of final prostate pathology with greater accuracy than that reported previously using conventional methods (81% vs 40% to 65%).

TL;DR: Deterioration after anterior 1-stage substitution urethroplasty seems to develop within the first 5 years, with oral mucosa showing greater failure-free survival than penile skin and 1- stage penile ure throatplasty showed the same success rate as bulbar ure Throplasty.