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Andrew J. Spence
Researcher at Temple University
Publications - 68
Citations - 2676
Andrew J. Spence is an academic researcher from Temple University. The author has contributed to research in topics: Image segmentation & Gait. The author has an hindex of 24, co-authored 66 publications receiving 2273 citations. Previous affiliations of Andrew J. Spence include University of California, Berkeley & Cornell University.
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Journal ArticleDOI
Brain responses to micro-machined silicon devices.
Donald H. Szarowski,M. D. Andersen,Scott T. Retterer,Andrew J. Spence,Michael Isaacson,Harold G. Craighead,James N. Turner,James N. Turner,William Shain,William Shain +9 more
TL;DR: Data indicate that device insertion promotes an early response proportional to device size and a sustained response that is independent of device size, geometry, and surface roughness, which may be associated with the amount of damage generated during insertion.
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Dexamethasone treatment reduces astroglia responses to inserted neuroprosthetic devices in rat neocortex.
L. Spataro,J. Dilgen,Scott T. Retterer,Andrew J. Spence,Michael Isaacson,James N. Turner,James N. Turner,William Shain,William Shain +8 more
TL;DR: The results suggest that anti-inflammatory agents can be used to control reactive responses around inserted neural prosthetic devices and may provide a means to insure their long-term function.
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Leveraging Elastic instabilities for Amplified Performance: spine-inspired high-speed and high-force soft robots
Yichao Tang,Yichao Tang,Yinding Chi,Jiefeng Sun,Tzu-Hao Huang,Omid Haji Maghsoudi,Andrew J. Spence,Jianguo Zhao,Hao Su,Jie Yin +9 more
TL;DR: This study establishes a new generic design paradigm of next-generation high-performance soft robots that are applicable for multifunctionality, different actuation methods, and materials at multiscales.
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Extracellular recordings from patterned neuronal networks using planar microelectrode arrays
Conrad D. James,Andrew J. Spence,Natalie Dowell-Mesfin,Rifat J. Hussain,K.L. Smith,Harold G. Craighead,Michael Isaacson,William Shain,James N. Turner +8 more
TL;DR: An extracellular recording from a -2 pm bundle of guided neurites is presented, and multichannel recordings detected instances of coincident firing activity.
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Model neural prostheses with integrated microfluidics: a potential intervention strategy for controlling reactive cell and tissue responses
Scott T. Retterer,K.L. Smith,CS Bjornsson,Keith B. Neeves,Andrew J. Spence,James N. Turner,William Shain,Michael Isaacson +7 more
TL;DR: Results indicate that diffusion-mediated delivery can be part of an effective intervention strategy for the treatment of reactive tissue responses around chronically implanted intracortical probes.