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Andrew Palma
Researcher at University of Massachusetts Amherst
Publications - 7
Citations - 539
Andrew Palma is an academic researcher from University of Massachusetts Amherst. The author has contributed to research in topics: Voltage-dependent calcium channel & Calcium channel. The author has an hindex of 5, co-authored 7 publications receiving 519 citations.
Papers
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Journal ArticleDOI
Selective peptide antagonist of the class E calcium channel from the venom of the tarantula Hysterocrates gigas.
Robert Newcomb,Balazs G. Szoke,Andrew Palma,Gang Wang,Xiao-hua Chen,William F. Hopkins,Cong Ruth,James A. Miller,Laszlo Urge,Katalin Tarczy-Hornoch,Joseph A. Loo,David J. Dooley,Laszlo Nadasdi,Richard W. Tsien,José R. Lemos,George P. Miljanich +15 more
TL;DR: The unique selectivity of SNX-482 suggests its usefulness in studying the diversity, function, and pharmacology of class E and/or R-type Ca2+ channels.
Journal ArticleDOI
SNX-325, a novel calcium antagonist from the spider Segestria florentina.
Robert Newcomb,Andrew Palma,J Fox,S. Gaur,K Lau,Daniel C. Chung,Cong Ruth,J.R. Bell,B Horne,Laszlo Nadasdi +9 more
TL;DR: SNX-325 will be a useful comparative tool in further defining the function and pharmacology of the N- and possibly other types of high-voltage activated calcium channels.
Journal ArticleDOI
Effects of diverse ω-conopeptides on the in vivo release of glutamic and γ-aminobutyric acids
Robert Newcomb,Andrew Palma +1 more
TL;DR: MVIIC provides a tool for investigating the role of calcium mediated release of glutamate and GABA in physiological and pathological processes in the mammalian brain in vivo and differences in potency were not explained by differential degradation.
Patent
Dna encoding a human calcium channel alpha-1e subunit
TL;DR: Isolated DNA encoding a human neuronal calcium channel alpha-1 subunit of subtype E and its corresponding polypeptide is disclosed in this article, as well as methods for screening for therapeutic compounds, using such compositions.
Patent
Voltage-gated calcium channel antagonist and methods
Robert Newcomb,Andrew Palma,Balazs G. Szoke,Katalin Tarczy-Hornoch,William F. Hopkins,Cong Ruth,George P. Miljanich,Robin Dean,Laszlo Nadasdi,Laszlo Urge,Stephen S. Bowersox +10 more
TL;DR: A novel class of peptides selectively block class E voltage-gated calcium channels as mentioned in this paper, which is exemplified by HG peptides such as HG-1, which was isolated from the venom-producing cells of the tarantula Hysterocrates gigas.