L
Laszlo Urge
Researcher at University of Massachusetts Amherst
Publications - 5
Citations - 471
Laszlo Urge is an academic researcher from University of Massachusetts Amherst. The author has contributed to research in topics: Calcium channel & Voltage-dependent calcium channel. The author has an hindex of 4, co-authored 5 publications receiving 454 citations.
Papers
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Journal ArticleDOI
Selective peptide antagonist of the class E calcium channel from the venom of the tarantula Hysterocrates gigas.
Robert Newcomb,Balazs G. Szoke,Andrew Palma,Gang Wang,Xiao-hua Chen,William F. Hopkins,Cong Ruth,James A. Miller,Laszlo Urge,Katalin Tarczy-Hornoch,Joseph A. Loo,David J. Dooley,Laszlo Nadasdi,Richard W. Tsien,José R. Lemos,George P. Miljanich +15 more
TL;DR: The unique selectivity of SNX-482 suggests its usefulness in studying the diversity, function, and pharmacology of class E and/or R-type Ca2+ channels.
Patent
Substituted peptidylamine calcium channel blockers
Lain Yen Hu,Thomas Charles Malone,Laszlo Nadasdi,Rafferty Michael Francis,Todd Robert Ryder,Diego F. Silva,Yuntao Song,Azoke Balazs G,Laszlo Urge +8 more
TL;DR: In this paper, the authors provided compounds that block calcium channels having the Formula I shown below. And they also provided methods of using the compounds of Formula I to treat stroke, cerebral ischemia, head trauma, or epilepsy and to pharmaceutical compositions that contain the compounds.
Patent
Peptidyl calcium channel blockers
Richard John Booth,Louis Brogley,Wayne L. Cody,David T. Connor,Harriet Wall Hamilton,John X. He,Lain-Yen Hu,Leonard Joseph Lescosky,Thomas Charles Malone,Laszlo Nadasdi,Michael Francis Rafferty,Bruce David Roth,Diego F. Silva,Yuntao Song,Balazs G. Szoke,Laszlo Urge +15 more
TL;DR: In this paper, the authors presented a method of using the compounds of Formula I to treat stroke, cerebral ischemia, head trauma, or epilepsy and to pharmaceutical compositions that contain the compounds.
Patent
Voltage-gated calcium channel antagonist and methods
Robert Newcomb,Andrew Palma,Balazs G. Szoke,Katalin Tarczy-Hornoch,William F. Hopkins,Cong Ruth,George P. Miljanich,Robin Dean,Laszlo Nadasdi,Laszlo Urge,Stephen S. Bowersox +10 more
TL;DR: A novel class of peptides selectively block class E voltage-gated calcium channels as mentioned in this paper, which is exemplified by HG peptides such as HG-1, which was isolated from the venom-producing cells of the tarantula Hysterocrates gigas.
Patent
Inhibiteurs des canaux de calcium de peptidylamine substituee
Lain-Yen Hu,Thomas Charles Malone,Laszlo Nadasdi,Michael Francis Rafferty,Todd Robert Ryder,Diego F. Silva,Yuntao Song,Balazs G. Szoke,Laszlo Urge +8 more
TL;DR: The authors concerne des composes inhibiteurs des canaux de calcium and representes par la formule (I), e.g., l'ischemie cerebrale, le traumatisme crânien ou l'epilepsie.