Laszlo Nadasdi

TL;DR: The unique selectivity of SNX-482 suggests its usefulness in studying the diversity, function, and pharmacology of class E and/or R-type Ca2+ channels.

TL;DR: The rate and extent of peptide-induced leakage of contents from large, unilamellar vesicles composed of egg phosphatidylcholine were dependent on pH, and changes in molar ellipticity were most significant over the same pH range where a maximum change in the extent and rate of leakage occurred.

TL;DR: Three neurotoxic peptides from the venom of Conus striatus have been purified, biochemically characterized, and chemically synthesized, and binding competition experiments with rat brain synaptosomal membranes indicate that the high-affinity binding site for omega-conotoxin SVIB is distinct from the high -affinity omega-Conotoxin GVIA or MVIIA site.

TL;DR: In this paper, the solution properties and bilayer association of two synthetic 30 amino acid peptides, GALA and LAGA, have been investigated at pH 5 and 7.5.

TL;DR: Q‐channels are present on a subset of the neurohypophysial terminals where, in combination with N‐ and L‐ch channels, they control AVP but not OT peptide neurosecretion.