Andrey Morgun

TL;DR: Evidence from 42 human studies reporting microbial associations with disease, and supporting preclinical studies or clinical trials using treatments with probiotics are identified, found the genera of Bifidobacterium, Bacteroides, Faecalibacteriaium, Akkermansia and Roseburia were negatively associated with T2D, while theGenera of Ruminococcus, Fusobacteria, and Blautia were positively associated withT2D.

TL;DR: In this article, a clinical trial evaluated the safety and efficacy of responder-derived fecal microbiota transplantation (FMT) together with anti-programmed cell death protein 1 (PD-1) therapy for patients with advanced melanoma.

TL;DR: Gene expression patterns in gut biopsies from individuals with common variable immunodeficiency or with HIV infection and intestinal malabsorption were very similar to those of the B cell–deficient mice, providing a possible explanation for a longstanding enigmatic association between immunodficiency and defective lipid absorption in humans.

TL;DR: A new bioinformatics approach is described that predicts microbial components that regulate host functions and establishes a comprehensive resource on what, why and how antibiotics affect the gut in a widely used mouse model of microbiota depletion by antibiotics.

TL;DR: It is shown that the gut microbe Akkermansia muciniphila can mediate negative effects of IFNγ on glucose tolerance in mice and humans, and Irgm1 is identified as anIFNγ-regulated gene in the mouse ileum that controls gut A. muc iniphila levels.