A
Anita H. J. van den Biggelaar
Researcher at University of Western Australia
Publications - 49
Citations - 2772
Anita H. J. van den Biggelaar is an academic researcher from University of Western Australia. The author has contributed to research in topics: Pneumococcal conjugate vaccine & Vaccination. The author has an hindex of 20, co-authored 47 publications receiving 2614 citations. Previous affiliations of Anita H. J. van den Biggelaar include Leiden University Medical Center & Albert Schweitzer Hospital.
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Journal ArticleDOI
Decreased atopy in children infected with Schistosoma haematobium: a role for parasite-induced interleukin-10.
Anita H. J. van den Biggelaar,Ronald van Ree,Laura C. Rodrigues,Bertrand Lell,André M. Deelder,Peter G. Kremsner,Maria Yazdanbakhsh +6 more
TL;DR: The anti-inflammatory cytokine, interleukin-10, induced in chronic schistosomiasis, appears central to suppressing atopy in African children.
Journal ArticleDOI
Long-Term Treatment of Intestinal Helminths Increases Mite Skin-Test Reactivity in Gabonese Schoolchildren
Anita H. J. van den Biggelaar,Anita H. J. van den Biggelaar,Laura C. Rodrigues,Ronald van Ree,Jaring S. van der Zee,Yvonne C. M. Hoeksma-Kruize,John H. M. Souverijn,Michel A. Missinou,Michel A. Missinou,Steffen Borrmann,Steffen Borrmann,Peter G. Kremsner,Peter G. Kremsner,Maria Yazdanbakhsh +13 more
TL;DR: A randomized controlled trial was performed to study whether repeated anthelminthic treatment results in increased allergic sensitivity to house dust mites (HDMs) in chronically infected children as mentioned in this paper.
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Th2 responses without atopy: immunoregulation in chronic helminth infections and reduced allergic disease
TL;DR: It is suggested that downregulatory immune mechanisms, which dampen the anti-parasite response, might benefit the host by blocking progression to atopic reactions, of relevance in explaining how the "hygiene hypothesis" might operate immunologically and in the design of therapeutics.
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Inflammation and interleukin-1 signaling network contribute to depressive symptoms but not cognitive decline in old age.
Anita H. J. van den Biggelaar,Jacobijn Gussekloo,Anton J. M. de Craen,Marijke Frölich,Max L. Stek,Roos C. van der Mast,Rudi G. J. Westendorp +6 more
TL;DR: It is shown that in old age inflammatory processes contribute to the development of depressive symptoms but not cognitive decline, and a high innate IL-1ra toIL-1beta production capacity reflects a better ability to neutralize inflammation and may therefore protect against depressive symptoms.
Journal ArticleDOI
Differences in innate immune function between allergic and nonallergic children: New insights into immune ontogeny
Meri K. Tulic,Megan Hodder,Anna Forsberg,Suzi McCarthy,Tara R. Richman,Nina D'Vaz,Anita H. J. van den Biggelaar,Catherine A. Thornton,Susan L. Prescott +8 more
TL;DR: Significant differences in the developmental trajectory of innate immune function in children with allergic disease that might contribute to the recognized differences in postnatal adaptive T-cell immunity are suggested.