A
Anita Lewit-Bentley
Researcher at Centre national de la recherche scientifique
Publications - 46
Citations - 2724
Anita Lewit-Bentley is an academic researcher from Centre national de la recherche scientifique. The author has contributed to research in topics: Binding site & Plasmodium falciparum. The author has an hindex of 24, co-authored 46 publications receiving 2616 citations. Previous affiliations of Anita Lewit-Bentley include Max Planck Society & University of Paris-Sud.
Papers
More filters
Journal ArticleDOI
EF-hand calcium-binding proteins.
TL;DR: Recently determined structures of members of several newly identified protein families that contain the EF-hand motif in some of their domains, as well as of their complexes with target molecules, are throwing light on the surprising variety of functions that can be served by this simple and ingenious structural motif.
Journal ArticleDOI
The crystal structure of a complex of p11 with the annexin II N-terminal peptide.
Stéphane Réty,Jana Sopkova,Madalena Renouard,Dirk Osterloh,Volker Gerke,Sébastien Tabaries,Françoise Russo-Marie,Anita Lewit-Bentley +7 more
TL;DR: The first structure of a complex between p11 and its cognate peptide, the N-terminus of annexin II, as well as that of p11 alone are reported, suggesting a model for an oxidized form of other S100 proteins that have been found in the extracellular milieu.
Journal ArticleDOI
Detergent structure in crystals of a bacterial photosynthetic reaction centre
M. Roth,Anita Lewit-Bentley,Hartmut Michel,Johann Deisenhofer,Robert Huber,Dieter Oesterhelt +5 more
TL;DR: In this paper, a low-resolution structure using neutron diffraction with contrast variation was generated to determine the structural motifs formed by the detergent that are involved in crystal packing, which provided insights into the mechanism of photo-activated electron transport across the cell membrane.
Journal ArticleDOI
Structural Basis of the Ca2+ Dependent Association between S100C (S100A11) and its Target, the N-Terminal Part of Annexin I
Stéphane Réty,Dirk Osterloh,Jean Philippe Arié,Sébastien Tabaries,Joachim Seeman,Françoise Russo-Marie,Volker Gerke,Anita Lewit-Bentley +7 more
TL;DR: By solving the structure of a second annexin N terminus-S100 protein complex, this work confirmed a novel mode of interaction of S100 proteins with their target peptides; there is a one-to-one stoichiometry, where the dimeric structure of the S100 protein is, nevertheless, essential for complex formation.
Journal ArticleDOI
Full-length extracellular region of the var2CSA variant of PfEMP1 is required for specific, high-affinity binding to CSA
Anand Srivastava,Stéphane Gangnard,Adam Round,Sébastien Dechavanne,Alexandre Juillerat,Bertrand Raynal,Grazyna Faure,Bruno Baron,Stéphanie Ramboarina,Saurabh Singh,Hassan Belrhali,Patrick England,Anita Lewit-Bentley,Artur Scherf,Graham A. Bentley,Benoit Gamain +15 more
TL;DR: It is suggested that a high-affinity, CSA-specific binding site is formed by the higher-order structure of the var2CSA extracellular region, which has important consequences for the development of an effective vaccine and therapeutic inhibitors.