A
Ann C. Collier
Researcher at Fred Hutchinson Cancer Research Center
Publications - 13
Citations - 1667
Ann C. Collier is an academic researcher from Fred Hutchinson Cancer Research Center. The author has contributed to research in topics: Reverse-transcriptase inhibitor & Acquired immunodeficiency syndrome (AIDS). The author has an hindex of 8, co-authored 13 publications receiving 1621 citations. Previous affiliations of Ann C. Collier include Research Triangle Park & Biogen Idec.
Papers
More filters
Journal ArticleDOI
Antiretroviral-Drug Resistance among Patients Recently Infected with HIV
Susan J. Little,Sarah Holte,Jean-Pierre Routy,Eric S. Daar,Marty Markowitz,Ann C. Collier,Richard A. Koup,John W. Mellors,Elizabeth Connick,Brian Conway,Michael Kilby,Lei Wang,Jeannette M. Whitcomb,Nicholas S. Hellmann,Douglas D. Richman +14 more
TL;DR: Testing for resistance to drugs before therapy begins is now indicated even for recently infected patients, as the proportion of new HIV infections that involve drug-resistant virus is increasing in North America.
Journal ArticleDOI
A multicenter observational study of the potential benefits of initiating combination antiretroviral therapy during acute HIV infection.
Frederick Hecht,Lei Wang,Ann C. Collier,Susan J. Little,Martin Markowitz,Joseph B. Margolick,J. Michael Kilby,Eric S. Daar,Brian Conway +8 more
TL;DR: Initiation of HAART within 2 weeks of antibody seroconversion was associated with viral load and CD4+ T cell count benefits for 24 weeks after termination ofHAART, with there being trends toward a longer-term benefit.
Journal ArticleDOI
Treatment of Primary Human Immunodeficiency Virus Type 1 Infection with Potent Antiretroviral Therapy Reduces Frequency of Rapid Progression to AIDS
M. Michelle Berrey,Timothy Schacker,Ann C. Collier,Theresa Shea,Scott J. Brodie,Douglas L. Mayers,Robert W. Coombs,John N. Krieger,Tae Wook Chun,Anthony S. Fauci,Steven G. Self,Lawrence Corey +11 more
TL;DR: Combination antiretroviral therapy during primary HIV-1 infection demonstrated a decreased frequency of minor opportunistic infections, mucocutaneous disorders, and respiratory infections and reduced progression to AIDS.
Journal ArticleDOI
Cryptosporidiosis After Marrow Transplantation: Person-to-Person Transmission and Treatment with Spiramycin
TL;DR: Excerpt Cryptosporidium has received increasing attention as a pathogen in normal as well as immunocompromised persons and may be acquired by contact with infected animals.
Journal ArticleDOI
Virus-Specific CD8+ T-Cell Responses Better Define HIV Disease Progression than HLA Genotype
Warren L. Dinges,Julia Richardt,David Friedrich,Emilie Jalbert,Yi Liu,Claire E. Stevens,Janine Maenza,Ann C. Collier,Daniel E. Geraghty,Jeremy Smith,Zoe Moodie,James I. Mullins,M. Juliana McElrath,Helen Horton +13 more
TL;DR: The presence of certain B57/58, B27-, and B35-restricted HIV-specific CD8+ T-cell responses after primary HIV-1 infection better defined disease progression than the HLA genotype alone, suggesting that vaccine immunogens should contain only conserved regions of HIV- 1.