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Anna Kraft
Researcher at Friedrich Loeffler Institute
Publications - 3
Citations - 46
Anna Kraft is an academic researcher from Friedrich Loeffler Institute. The author has contributed to research in topics: Neutralizing antibody & Viral load. The author has an hindex of 3, co-authored 3 publications receiving 14 citations.
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Journal ArticleDOI
CVnCoV and CV2CoV protect human ACE2 transgenic mice from ancestral B BavPat1 and emerging B.1.351 SARS-CoV-2.
Donata Hoffmann,Björn Corleis,Susanne Rauch,Nicole Roth,Janine Mühe,Nico Joel Halwe,Lorenz Ulrich,Charlie Fricke,Jacob Schön,Anna Kraft,Angele Breithaupt,Kerstin Wernike,Anna Michelitsch,Franziska Sick,Claudia Wylezich,Bernd Hoffmann,Moritz Thran,Andreas Thess,Stefan O. Mueller,Thomas C. Mettenleiter,Benjamin Petsch,Anca Dorhoi,Martin Beer +22 more
TL;DR: In this paper, spike encoding mRNA vaccines (CVnCoV and CV2CoV) against the ancestral strain and the VOC B.1.351 was tested in a K18-hACE2 transgenic mouse model.
Posted ContentDOI
Enhanced fitness of SARS-CoV-2 variant of concern B.1.1.7, but not B.1.351, in animal models
Lorenz Ulrich,Nico Joel Halwe,Adriano Taddeo,Nadine Ebert,Jacob Sch oumln,Christelle Devisme,Bettina Salome Tr uumleb,Bernd Hoffmann,Manon Wider,Meriem Bekliz,Manel Essaidi-Laziosi,Marie Luisa Schmidt,Daniela Niemeyer,Victor M. Corman,Anna Kraft,Aur eacutelie Godel,Laura Laloli,Jenna N. Kelly,Angele Breithaupt,Claudia Wylezich,In ecircs Margarida Berenguer Veiga,Mitra Gultom,Kenneth Adea,Benjamin Meyer,Christiane S Eberhardt,Christiane S Eberhardt,Lisa Thomann,Monika Gsell-Albert,Fabien Labroussaa,J oumlrg Jores,Artur Summerfield,Christian Drosten,Isabella Eckerle,Isabella Eckerle,Ronald Dijkman,Donata Hoffmann,Volker Thiel,Martin Beer,Charaf Benarafa +38 more
TL;DR: In this article, the authors assessed VOC B.1.7 and found that the VOC had similar replication kinetics as compared to wt-S614G in human airway epithelial cultures.
Posted ContentDOI
CVnCoV protects human ACE2 transgenic mice from ancestral B BavPat1 and emerging B.1.351 SARS-CoV-2
Donata Hoffmann,Bjoern Corleis,Susanne Rauch,Nicole Roth,Janine Muehe,Nico Joel Halwe,Lorenz Ulrich,Charlie Fricke,Jacob Schoen,Anna Kraft,Angele Breithaupt,Kerstin Wernike,Anna Michelitsch,Franziska Sick,Claudia Wylezich,Stefan O. Mueller,Thomas C. Mettenleiter,Benjamin Petsch,Anca Dorhoi,Martin Beer +19 more
TL;DR: CVnCoV vaccine completely protected the animals from disease and mortality caused by either viral strain, and was not detected in oral swabs, lung, or brain in these groups, while only partial protection was observed in mice receiving the formalin-inactivated virus preparation.