Anthony Pierre

TL;DR: Bone marrow cells secrete angiogenic factors that induce endothelial cell proliferation and, when injected transendocardially, augment collateral perfusion and myocardial function in ischemic myocardium.

TL;DR: If it is determined that direct intramyocardial injection of angiogenic factors enhances collateral function in patients, this less invasive catheter-based system offers a similar gene delivery efficiency and, thus, may have clear advantages compared with the surgically-based transepicardial injection approach.

TL;DR: An electromechanical left ventricular mapping procedure such as the one described here may be of diagnostic value for identifying the hibernating myocardium.

TL;DR: It is concluded that using this magnetic guidance catheter‐based navigational system, it is feasible and safe to perform the transendocardial injection procedure and offers a clear advantage over surgically based transepicardial injection procedures.

TL;DR: Catheter-based left ventricular assessment of electromechanical activity correlates with the degree of single-photon emission computed tomographic perfusion abnormality and can identify myocardial viability with a greater accuracy than myocardIAL ischemia.