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Anton Pozniak
Researcher at Imperial College London
Publications - 270
Citations - 13961
Anton Pozniak is an academic researcher from Imperial College London. The author has contributed to research in topics: Ritonavir & Acquired immunodeficiency syndrome (AIDS). The author has an hindex of 53, co-authored 241 publications receiving 13079 citations. Previous affiliations of Anton Pozniak include Oxleas NHS Foundation Trust & Bristol-Myers Squibb.
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Journal ArticleDOI
HIV treatment cascades: how can all countries reach the UNAIDS 90-90-90 target?
Andrew F. Hill,Anton Pozniak +1 more
TL;DR: It is likely that at least 35 million people would need to be on treatment by 2020 to include newly infected people in the 90-90-90 targets.
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Prioritising the most needed paediatric antiretroviral formulations: the PADO4 list
Martina Penazzato,Claire L Townsend,Natella Rakhmanina,Natella Rakhmanina,Natella Rakhmanina,Yao Cheng,Moherndran Archary,Tim R Cressey,Tim R Cressey,Tim R Cressey,Maria H Kim,Victor Musiime,Anna Turkova,Theodore Ruel,Helena Rabie,Nandita Sugandhi,Pablo Rojo,Meg Doherty,Elaine J. Abrams,Elaine J. Abrams,Jintanat Ananworanich,Isabelle Andrieux-Meyer,Yodit Belew,Brookie M. Best,Rosa Bologna,Jessica Burry,Deborah Carpenter,Polly Clayden,Angela Colbers,Magda Conway,Tim R. Cressey,Mutsa Dangarembizi,Shaffiq Essajee,Maribel Gonzalez Tome,Andrew F. Hill,Saye Khoo,Maria Kim,Linda Lewis,Janice Lee,Shahin Lockman,Imelda Mahaka,Mark Mirochnick,Lynne M. Mofenson,Mireille Muhimpundu,Angela Mushavi,Elizabeth Obimbo,Fernando Pascual,Carmen Perez Casas,Anton Pozniak,Theodore Ruel,Jonathan M. Schapiro,George K. Siberry,Teresa Beatriz Simione,Cheick Tidiane Tall,Francois Venter,Marissa Vicari,Jenny Walsh,Jacque Wambui,Melynda Watkins +58 more
TL;DR: The Paediatric Antiretroviral Drug Optimization group reviews medium-term and long-term priorities for antireTroviral drug development to guide industry and other stakeholders on formulations most needed for low-income and middle-income countries.
Journal ArticleDOI
The SPICE study: 48-week activity of combinations of saquinavir soft gelatin and nelfinavir with and without nucleoside analogues. Study of Protease Inhibitor Combinations in Europe.
Graeme Moyle,Anton Pozniak,Milos Opravil,Nathan Clumeck,Jean-François Delfraissy,Margaret A. Johnson,Jolanda Pelgrom,Jacques Reynes,Daniel Vittecoq,Patricia Delora,Miklos Salgo,Frank Duff +11 more
TL;DR: Quadruple therapy gave a more durable response than triple therapy with either single protease inhibitor and might particularly benefit NRTI-experienced patients and those with high baseline viral loads.
Journal ArticleDOI
Sequential Population Pharmacokinetic Modeling of Lopinavir and Ritonavir in Healthy Volunteers and Assessment of Different Dosing Strategies
Laura Dickinson,Marta Boffito,David Back,Laura Else,Nils von Hentig,Geraint Davies,Saye Khoo,Anton Pozniak,Graeme Moyle,Leon Aarons +9 more
TL;DR: Nonlinear mixed-effects modeling allows a better understanding of the interaction between lopinavir and ritonavir and may allow a better prediction of lopvinir concentrations and assessments of different dosing strategies.
Journal ArticleDOI
The development of an expert system to predict virological response to HIV therapy as part of an online treatment support tool.
Andrew D. Revell,Dechao Wang,Mark A. Boyd,Sean Emery,Anton Pozniak,Frank de Wolf,Richard Harrigan,Julio S. G. Montaner,Clifford Lane,Brendan Larder +9 more
TL;DR: The development and testing of random forest models to power an online treatment selection tool and achieved a consistent, high level of accuracy in predicting treatment responses, which was markedly superior to that of genotypic sensitivity scores.