A
Antonio Nakouzi
Researcher at Albert Einstein College of Medicine
Publications - 44
Citations - 2298
Antonio Nakouzi is an academic researcher from Albert Einstein College of Medicine. The author has contributed to research in topics: Cryptococcus neoformans & Antibody. The author has an hindex of 23, co-authored 41 publications receiving 2032 citations. Previous affiliations of Antonio Nakouzi include Yeshiva University & Montefiore Medical Center.
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Journal ArticleDOI
Vesicular Polysaccharide Export in Cryptococcus neoformans Is a Eukaryotic Solution to the Problem of Fungal Trans-Cell Wall Transport
Marcio L. Rodrigues,Leonardo Nimrichter,Débora L. Oliveira,Susana Frases,Kildare Miranda,Oscar Zaragoza,Mauricio A. Álvarez,Antonio Nakouzi,Marta Feldmesser,Arturo Casadevall +9 more
TL;DR: It is demonstrated that C. neoformans produces extracellular vesicles during in vitro growth and animal infection and implies a novel mechanism for the release of the major virulence factor of C. Neoformans whereby polysaccharide packaged in lipid vesicle crosses the cell wall and the capsule network to reach the Extracellular environment.
Journal ArticleDOI
Bacillus anthracis produces membrane-derived vesicles containing biologically active toxins
Johanna Rivera,Radames J. B. Cordero,Antonio Nakouzi,Susana Frases,André Moraes Nicola,André Moraes Nicola,Arturo Casadevall +6 more
TL;DR: The results indicate that toxin secretion in B. anthracis is, at least, partially vesicle-associated, thus allowing concentrated delivery of toxin components to target host cells, a mechanism that may increase toxin potency.
Journal ArticleDOI
Experimental Diabetes Is Associated With Functional Activation of Protein Kinase Cε and Phosphorylation of Troponin I in the Heart, Which Are Prevented by Angiotensin II Receptor Blockade
Ashwani Malhotra,David Reich,Daniel Reich,Antonio Nakouzi,Vinay Sanghi,David L. Geenen,Peter M. Buttrick +6 more
TL;DR: The data suggest that angiotensin II receptor-mediated activation of PKC may play a role in the contractile dysfunction seen in chronic diabetes.
Journal ArticleDOI
Self-Aggregation of Cryptococcus neoformans Capsular Glucuronoxylomannan Is Dependent on Divalent Cations‡
Leonardo Nimrichter,Susana Frases,Leonardo Paes Cinelli,Nathan B. Viana,Antonio Nakouzi,Luiz R. Travassos,Arturo Casadevall,Marcio L. Rodrigues +7 more
TL;DR: It is shown that concentration of C. neoformans culture supernatants by ultrafiltration results in the formation of highly viscous films containing pure polysaccharide, providing a novel, nondenaturing, and extremely rapid method to isolate extracellular GXM.
Journal ArticleDOI
Cardiac adaptations to chronic exercise in mice
M. L. Kaplan,Y. Cheslow,Karen L. Vikstrom,Ashwani Malhotra,David L. Geenen,Antonio Nakouzi,Leslie A. Leinwand,Peter M. Buttrick +7 more
TL;DR: It is established that mice are able to develop cardiac hypertrophy in response to chronic conditioning which is not associated with changes in the ATPase activities of cardiac muscle.