A
Antony Vinh
Researcher at La Trobe University
Publications - 84
Citations - 5120
Antony Vinh is an academic researcher from La Trobe University. The author has contributed to research in topics: Angiotensin II & Inflammation. The author has an hindex of 32, co-authored 70 publications receiving 3987 citations. Previous affiliations of Antony Vinh include University of Otago & Emory University.
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Journal ArticleDOI
Inflammation, Immunity, and Hypertension
David G. Harrison,Tomasz J. Guzik,Heinrich E. Lob,Meena S. Madhur,Paul J. Marvar,Salim R. Thabet,Antony Vinh,Cornelia M. Weyand +7 more
TL;DR: Components of the innate and adaptive immune response are reviewed, data from many groups are discussed that suggest that common forms of hypertension are immune mediated, and a working hypothesis of how signals from the central nervous system trigger an immune response that causes hypertension is provided.
Journal ArticleDOI
DC isoketal-modified proteins activate T cells and promote hypertension
Annet Kirabo,Vanessa Fontana,Ana Paula Faria,Roxana Loperena,Christi L Galindo,Jing Wu,Alfiya T Bikineyeva,Sergey Dikalov,Liang Xiao,Wei Chen,Mohamed A. Saleh,Daniel W. Trott,Hana A. Itani,Antony Vinh,Venkataraman Amarnath,Kalyani Amarnath,Tomasz J. Guzik,Kenneth E. Bernstein,Xiao Z. Shen,Yu Shyr,Sheau-Chiann Chen,Raymond L. Mernaugh,Cheryl L. Laffer,Fernando Elijovich,Sean S. Davies,Heitor Moreno,Meena S. Madhur,L. Jackson Roberts,David G. Harrison +28 more
TL;DR: The data reveal that hypertension activates dendritic cell activation of T cells, in large part by promoting the formation of isoketals, and suggest that reducing isokets has potential as a treatment strategy for this disease.
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Inhibition and Genetic Ablation of the B7/CD28 T cell Costimulation Axis Prevents Experimental Hypertension
Antony Vinh,Wei Chen,Yelena Blinder,Daiana Weiss,W. Robert Taylor,Jörg J. Goronzy,Cornelia M. Weyand,David G. Harrison,Tomasz J. Guzik +8 more
TL;DR: T-cell costimulation via B7 ligands is essential for development of experimental hypertension, and inhibition of this process could have therapeutic benefit in the treatment of this disease.
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AT2 receptors: Functional relevance in cardiovascular disease
TL;DR: During cardiovascular disease, there is likely to be an increased functional importance of AT2R, stimulated by Ang II, or even shorter angiotensin peptide fragments, to limit AT1R-mediated overactivity and cardiovascular pathologies.
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Role of Interleukin 17 in Inflammation, Atherosclerosis, and Vascular Function in Apolipoprotein E–Deficient Mice
Meena S. Madhur,Samuel A. Funt,Li Li,Antony Vinh,Wei Chen,Heinrich E. Lob,Yoichiro Iwakura,Yelena Blinder,Ayaz Rahman,Arshed A. Quyyumi,David G. Harrison +10 more
TL;DR: IL17 contributes to vascular and systemic inflammation in experimental atherosclerosis but does not alter plaque burden, and the changes in plaque composition caused by IL17 might modulate plaque stability.